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Database: UniProt
Entry: H2TIR2_TAKRU
LinkDB: H2TIR2_TAKRU
Original site: H2TIR2_TAKRU 
ID   H2TIR2_TAKRU            Unreviewed;       765 AA.
AC   H2TIR2;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   22-NOV-2017, entry version 31.
DE   SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2a {ECO:0000313|Ensembl:ENSTRUP00000024564};
GN   Name=LOC101078901 {ECO:0000313|Ensembl:ENSTRUP00000024564};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000024564, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000024564}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000024564}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTRUP00000024564}.
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DR   Ensembl; ENSTRUT00000024663; ENSTRUP00000024564; ENSTRUG00000009776.
DR   GeneTree; ENSGT00550000074513; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR020969; Ankyrin-G_BS.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR003947; K_chnl_volt-dep_KCNQ2.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 2.
DR   PANTHER; PTHR11537:SF6; PTHR11537:SF6; 2.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   Pfam; PF11956; KCNQC3-Ank-G_bd; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01461; KCNQ2CHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     28     48       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     60     81       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    102    120       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    166    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    228    253       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       32    253       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      342    540       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   765 AA;  85304 MW;  8DD5103E2642C8D5 CRC64;
     RPTKKNASYR KLQNFLYNAL ERPRGWAFVY HAYVFLLVFS CLILSVFATI KEFKNSSESA
     LYILEIVTIV VFGVEYIVRI WSAGCCCRYR GWRGRLKFAR KPFCVIDIMV LIASVSVLAA
     GSQGNIFATS AIRSLRFLQI LRMLRMDRRG GTWKLLGSVV YAHSKELITA WYIGFLCLIL
     ASFLVYSVEK ESNEEFETYA DALWWGLITL TTIGYGDKVP KTWNGRMLGA AFSMIGVAFF
     ALPAGILGSG FALKVQEQHR QKHFEKRRNP AAGLIQGAWR FYATNLSRTD LVCTWDFYEQ
     TVSVPMYSKE SLLAVCSRKA SLKDKVFPSP SKAPFAKGKA QSPGAEEGVE ASPYKVAKSW
     SFTDKNRGTK NSFKARGSTS RQNSEEASLP GEEMGDDKSC HCEFLTQELP SSLKVTIRAI
     CIMKFLVSKR KFKESLRPYD VMDVIEQYSA GHLDMLCRIK NLQTRIDMIV GPPPPSTPRH
     KKSTEGLAFS QIVGKSPKAD GDPGDDLSMM GRLVKVEKQV LCMDRKLDFL VNVYVQRMGI
     THSETEAYFN SKEPYPAPPY HSPDDSKLEK DNKEQMKEEK EVKTCSALDV PYSDSSLEQK
     DPLVGRSGAR SVGSPSASQS RPSTSWQHQL QHPLSQPAWN SSVANTPSPV CGDQSPNLFR
     LPPPPAPAHD RSSGSSSHSR RRRRRQTCQQ DGTAAESDTS LSIPSVDHEE LERSFSGFSI
     SQAKEDFFGP SFFAGTAGVR PFIAEGESDT DSDLYAPSPV SFTGD
//
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