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Database: UniProt
Entry: H2TV32_TAKRU
LinkDB: H2TV32_TAKRU
Original site: H2TV32_TAKRU 
ID   H2TV32_TAKRU            Unreviewed;       886 AA.
AC   H2TV32;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   25-OCT-2017, entry version 42.
DE   SubName: Full=Potassium voltage-gated channel, subfamily H (eag-related), member 4b {ECO:0000313|Ensembl:ENSTRUP00000028541};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000028541, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000028541}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000028541}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTRUP00000028541}.
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DR   Ensembl; ENSTRUT00000028655; ENSTRUP00000028541; ENSTRUG00000011301.
DR   GeneTree; ENSGT00900000140833; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR003950; K_chnl_volt-dep_ELK.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   PRINTS; PR01465; ELKCHANNEL.
DR   SMART; SM00100; cNMP; 1.
DR   SMART; SM00086; PAC; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00903208};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00904256};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00903350};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00903851}.
FT   TRANSMEM    225    245       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    310    333       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    354    380       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    449    475       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       22     90       PAS. {ECO:0000259|PROSITE:PS50112}.
FT   DOMAIN       93    145       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      553    653       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   COILED      850    877       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   886 AA;  99998 MW;  76930E77961C3F95 CRC64;
     MPVMKGLLAP QNTFLDAIAT RFDGTHSNFL LGNAQGHRGY PIVYCSDGFC ELTGFTRTEV
     MQKNCGCHFL FGADTSEHVA QQMLKALEGR EEYQAEVYFY KKNGVAFWCL LDIVPIKNEK
     GEMVLFLFSF KDISDMHGRG NHNSKKDGTE DKRHRRKNGS RFTEARKRGR TMLYHLTSQF
     SRGGKRELSI KRNSMIDKPS MPEYKVAAVQ KSRFILLHYS VSKALWDWLI LLATFYVAVT
     VPYNVSFTPY EDTVTAARST IVSDIVVEML FILDIILNFR TTYVSQSGQV VYESRSICIH
     YVRTWFFVDL VAALPFDLLY AFNITVTSLV HLLKTVRLLR LLRLLQKLDR YSQYSAMVLT
     LLMSMFALLA HWMACIWYMI GRKEIETNET WEIGWLHELG KRLETPYINS TLGGPTVRSS
     YIAALYFTLS SLTSVGFGNV SANTDAEKIF SICTMLVGGI ALMHALVFGN VTAIIQRMYS
     RRSLYHTRMK DLKDFIRVHR LPQQIKQRML EYFQTTWSVN NGIDANELLH DFPDELRADI
     AMHLNKDILQ LPVFKGASRG CLRSLSLHIK TSFCVPGEYL IRQGDALHAN YFVCSGSLEV
     LKDSMVLAIL GKGDLIGSDL PGTDQVIKTN ADVKALTYCD LQYIGLRGLR EVLELYPEYA
     NVFASDIYNN LTYNLREGSQ DEVRNRDLNK EKAHPSICKT HSNLKEPRLP SIVETTGDNS
     DDSFHLSPAT RSRRNLLLPS LSSPVRRTSL GNLLGQLSSP QPPPKKDHNT PSFTPASVQR
     GADAEQKPTK LLIPTVTCFG PPDLSPRVVD GIEDNGHTFH FNGEGSGPKA STGGSTRESS
     QANATLLLES EEVRQGISEL NHKMETLNQE VSELTKGLHH IMHILQ
//
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