ID H2U6J6_TAKRU Unreviewed; 691 AA.
AC H2U6J6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Solute carrier family 26 member 10-like {ECO:0000313|Ensembl:ENSTRUP00000032562.3};
GN Name=LOC101063563 {ECO:0000313|Ensembl:ENSTRUP00000032562.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000032562.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000032562.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000032562.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
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DR AlphaFoldDB; H2U6J6; -.
DR STRING; 31033.ENSTRUP00000032562; -.
DR Ensembl; ENSTRUT00000032687.3; ENSTRUP00000032562.3; ENSTRUG00000012857.3.
DR eggNOG; KOG0236; Eukaryota.
DR GeneTree; ENSGT01070000253775; -.
DR InParanoid; H2U6J6; -.
DR OMA; TECQKIG; -.
DR OrthoDB; 1067648at2759; -.
DR TreeFam; TF313784; -.
DR Proteomes; UP000005226; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF273; SOLUTE CARRIER FAMILY 26 MEMBER 10; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 70..86
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 126..144
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 164..189
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 403..423
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 457..482
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 513..675
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 691 AA; 76080 MW; 9E33B84D61340CB6 CRC64;
MSASVAVYRN IYTEDRFQQD YGSDDNAGGS PGLRERLASG CRCSRRACLH LLRDRVPIFN
WLPKYRLKKW ILGDTVAGLT VGILHIPQGM AFALLTSVAP IFGLYTSFFP VFLYMCFGTG
RHVSTGTFAV VSLMTGSVVE QLVPTPLEMN TSLPAAAEFE AQRIGVASAV ALLSGIIMLC
MFGLQLGFLS TYLSEPIVKA FTSAAAFHVT VSQLQSMLGL RLPRHTGTFS LFKTLGSVVE
NLPHTNTAEL LISLVCLAAL VPVKEINIRF RRRLRTPIPV EILTVIIATG VTFAASLDTN
YNIEIVGHIP AGFPKPKLPA LHTFPDIAGD TVAITFVGYA VSVSLAMIYA DKHGYSIHPN
QELLAHGISN TVSSFFTCFP SSATLATTNI LESAGGHTQL SGLFTSLVVL IVLLLIGPLF
YFLPKAVLAC INVTSLRQMF LQFQDLPELW KISKIDFMVW VVTWLSVVVL NVDLGLAIGV
VFSMMTVICR TQRAGCSVLG RASNTEIYRP MEKHSKCYEV PGVKILTYNG PIYYGNRNFF
REEMSRLLGL TPEKIRSWEK ARKALEKREG ETTVNTVERG IANTSFSSEN EFFKSETVES
DIQAVLIDCS SVIFVDVAGG RLFTQICTDC QKVGVCVYLA NCNESVLKIL TSSGLMNYMN
PQHIFVTVHD AVLYIQQQKE KPRESTTTVW V
//
