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Database: UniProt
Entry: H2U9E2_TAKRU
LinkDB: H2U9E2_TAKRU
Original site: H2U9E2_TAKRU 
ID   H2U9E2_TAKRU            Unreviewed;       595 AA.
AC   H2U9E2;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   25-OCT-2017, entry version 34.
DE   SubName: Full=Transient receptor potential cation channel, subfamily C, member 6b {ECO:0000313|Ensembl:ENSTRUP00000033558};
GN   Name=LOC101067110 {ECO:0000313|Ensembl:ENSTRUP00000033558};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000033558, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000033558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000033558}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTRUP00000033558}.
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DR   Ensembl; ENSTRUT00000033684; ENSTRUP00000033558; ENSTRUG00000013189.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   GeneTree; ENSGT00760000119180; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005462; TRPC6_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   PANTHER; PTHR10117:SF7; PTHR10117:SF7; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    321    341       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    353    376       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    404    421       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    442    466       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    549    571       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       20    101       ANK_REP_REGION. {ECO:0000259|Pfam:
FT                                PF12796}.
FT   DOMAIN      166    228       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      394    581       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   595 AA;  67728 MW;  02421368E9FDF5CF CRC64;
     MILNKHRESM FIQTEDHFLD AAENGNVPKV VQMLAELPDL NVNYVNCKGQ NALQLAVANE
     RLEVTKRLLK KKDLTRIGDA LLLAISKGYV RIVEALLSHQ AFLDGQRLSD CLSQSDDDFF
     TFDEDGTRFS RDITPIILAS QCHQYEMVHI LLMKGARIER PHDYFCQCRA CSDEQSRDSF
     SHSQSRINAY KGLASPAYLC LSSEDPVMEA LELGNELSIL ANTEKEFKND YTNLSTQCKD
     FVVGLLDLCR NTEEVKAILN GDAESCQNAD TSCRQNLYRL KLAIRYEVKK FVAHPNCQQQ
     LLSIWYEDLS GVRQQNTAVK ILLVLGVAAG LPVLAFIYWL APSSKLGKLM HGPFLKFVAH
     AASFIIFLCL LVLNGIDRFG GTSLLPNMTT RDHPLQLFRM KTTPFTWMEI LIISWVTGNI
     WKGCKEIWVQ DIGEYMSEPW NLLDFSILAT FMASFIARLM AFWHAYSAQC YIDKHYSDLA
     NMNLPFEIQY FQLARIDWLP SDPQLISEGL YAVAVVLSFS RIAYILPANE SFGPLQISLG
     RTVKDIFKFM VIFTTVFVAF MVGMFSLYSY YLGVKYNNAF TTYIFSINMT EDNES
//
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