ID H2UK61_TAKRU Unreviewed; 721 AA.
AC H2UK61;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Ankyrin repeat and kinase domain containing 1 {ECO:0000313|Ensembl:ENSTRUP00000037332.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000037332.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000037332.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000037332.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2UK61; -.
DR Ensembl; ENSTRUT00000037467.3; ENSTRUP00000037332.3; ENSTRUG00000014611.3.
DR GeneTree; ENSGT00940000162060; -.
DR Proteomes; UP000005226; Chromosome 11.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR24203; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24203:SF45; DIEGO, ISOFORM A; 1.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 9.
DR PROSITE; PS50088; ANK_REPEAT; 10.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 29..286
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 366..398
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 399..431
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 432..464
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 467..499
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 500..532
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 533..565
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 566..598
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 599..631
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 633..665
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 666..698
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 721 AA; 79446 MW; 64990D2D144B103E CRC64;
SLLINPCVHM DFTDGFPGHF GNFAKDEFEA DWTKMAECRF SHVYEVKLKA WQEKCVLKCF
HPPVKIINEV SKIAKVKFKY IVAIYGVCSE ATAVVMEHMS NGSLNNLLAS HTLMWPKKFQ
MVHEISMGVN FLHSMNPPIL HLNLKTSNIL LDDHLHAKIS DFALIHWEEG MSKTLFMESL
TARGNISYIP PETFTQSSDP PGTASDVYSF GIIIWEILTQ QKPYAGWSMT TVLLQVSQGR
RPCLEIIPEW RPNECDRIIC MMKQCWDQEP RKRPQFSDIV KTTESLCEVL KIPGSIQYEK
LEKDNILSFL SRKDFGSFRQ SLKQEHVHTV YTGKNSLLHY TVTSKDAASV EHVLNLGADI
NATTAQGYTP LIVAVLHRLH DIISLLLEHG AVVGHGDEDQ WTALHFAAQN GDDRTVRLLL
DKGAVVDARE RAGWMPLHLA CQNGHEPVVR LLLSRMSEEA VGEREGHGRT PLHMASAYGH
LSIAKLLLSQ GADPNATDGS LSTPLHLSAE EGHNRVVRQL LKSGVATDSA NSQGYNPLHL
AALKGHTGIC RQLLSNGANP DCTTLQAWTP MHLAALKGNE AIVVQLVCNG GSTNAKSENG
WTPLHLACHQ SEPEVTSVLL EAAADPNATE ASKGWSPLHF ACNSVSFQCV LHLIAHHADV
NALSFGKAAP LHVAIQHGCV PIVKTLLLNG ADKSLLDSSG SSALDVAKRC EKLEIVQLLE
S
//
