ID   H2UP48_TAKRU            Unreviewed;       719 AA.
AC   H2UP48;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Mitotic arrest deficient 1 like 1 {ECO:0000313|Ensembl:ENSTRUP00000038719.3};
GN   Name=mad1l1 {ECO:0000313|Ensembl:ENSTRUP00000038719.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000038719.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000038719.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000038719.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MAD1 family.
CC       {ECO:0000256|ARBA:ARBA00008029}.
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DR   AlphaFoldDB; H2UP48; -.
DR   STRING; 31033.ENSTRUP00000038719; -.
DR   Ensembl; ENSTRUT00000038858.3; ENSTRUP00000038719.3; ENSTRUG00000015158.3.
DR   GeneTree; ENSGT00390000001316; -.
DR   InParanoid; H2UP48; -.
DR   OMA; YKLDFMP; -.
DR   OrthoDB; 8224at2759; -.
DR   Proteomes; UP000005226; Chromosome 17.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.30.457.60; -; 1.
DR   Gene3D; 6.10.250.90; -; 1.
DR   InterPro; IPR008672; Mad1.
DR   PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR   PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR   Pfam; PF05557; MAD; 1.
DR   SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   COILED          93..242
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          266..317
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          432..579
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   719 AA;  83851 MW;  C2058190BA88A7F4 CRC64;
     MDLEDDTTVL TTLKSFNSFI SRTEPQQRLT ERPGSGTLQG QYKRSMELLE AADRLNSTNR
     YLQLDQEKKQ MELSHKRARF ELEKTASDRT RALEHEVDRN QELLTQIKKL KERESEMERN
     LTEKGDANRA LWKNLEALNK KLEDRDGRLS SANQTVSTLK DEVRELKQKI QNQDCTICAQ
     TLENQELQEQ LDLQRRKYQD VSQLYQSLQA TQSTCSDHVI KIKELERRLA LQEQDVAIMK
     TVKSELARVP GMEKELKNLR GDNSFLRESR ENCSLLKEEV EGLRKKLERM EKMKEDLVNM
     ELEKNRMAEK LQAWENLGQS TGLNIRKPED LSREVIQIQQ REFALKEQNY TLNSRVRSAE
     RSHSDVCAEL SEQRGKTLEE KKKRELQDTL VRRLQKRLML LNKERDGMRA ILESYDSELG
     STEYSPQLSK RLKEAEDVLQ RTQNHNVELE AELNKTHKEM GTLKLQLQTV ELELESVKKQ
     HAANADSSCS ATKEELSILR QKIEDLEADR QRLEEQNNNL EMRLERHNLQ GDYDPLKTRV
     LHLKMNPTSV AKQQRQQEME TIQEEVTRLR ELVRSLQDGG SLVQSQDDSI VPNLGLGLPP
     SKEVLDLRKQ MESSELKNQR LKEVFQRKIQ EFRTVCYILT GYQMDITTEN QYRLTSVYAE
     HMDDSLLFKK GSNGSMQLME TEFSKTLGEM VSLHLHHQKS IPAFLSAVTL DLFSRQTTI
//