ID   H2URZ0_TAKRU            Unreviewed;       771 AA.
AC   H2URZ0; H2URZ2;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Ribosomal protein S6 kinase like 1 {ECO:0000313|Ensembl:ENSTRUP00000039713.3};
GN   Name=RPS6KL1 {ECO:0000313|Ensembl:ENSTRUP00000039713.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000039713.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000039713.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000039713.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 31033.ENSTRUP00000039713; -.
DR   Ensembl; ENSTRUT00000039854.3; ENSTRUP00000039713.3; ENSTRUG00000015530.3.
DR   Ensembl; ENSTRUT00000039856.3; ENSTRUP00000039715.3; ENSTRUG00000015530.3.
DR   eggNOG; KOG0603; Eukaryota.
DR   GeneTree; ENSGT00940000159815; -.
DR   HOGENOM; CLU_014272_0_0_1; -.
DR   OMA; TFRSDWW; -.
DR   OrthoDB; 5308056at2759; -.
DR   TreeFam; TF323964; -.
DR   Proteomes; UP000005226; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   CDD; cd02677; MIT_SNX15; 1.
DR   Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR007330; MIT_dom.
DR   InterPro; IPR036181; MIT_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   PANTHER; PTHR15508; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR   PANTHER; PTHR15508:SF4; RIBOSOMAL PROTEIN S6 KINASE-LIKE 1; 1.
DR   Pfam; PF04212; MIT; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00745; MIT; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF116846; MIT domain; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   DOMAIN          458..761
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          217..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          383..409
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          428..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          519..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        217..233
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   771 AA;  84852 MW;  C7DA57D853E38452 CRC64;
     MAKRDYLVEA AKQFRMALDS EVSEDYEAAF SYYKNGVDLL LNGVQLDPNK ERREAVKRKT
     TQYLKRAEEI FITHLQDNLV KGSSHLGGYS SLRFRPIRHL SSPVEDLDMC KVVGVTDKVL
     IVQSMVNKET FVVKSLVKSS WESRDQPTII PQGVPYMVKL LRYYVSEDAV YLHLEHVKGG
     RLFSKLHKLR NEKAREHPEC LASGQHNAKL KTSYTSPTIS TDYQHNSGGS TGGIRDKPND
     ESPDAEFPTS WDETQRVESC RTHSYIEETG CLQNTRSAAS FYSKLERLTL YSGSSGAQVN
     TRIHPPAPSL CLHSSETQEH PALPLPCARV SLALNSMSDV NPTRAGMGLT ECSSEFEEAW
     KAADPAKNCE IINPYAVTDT GALGQTTPHT SQTSFLKGGS ASGSNNGLSS SPAVLHLPLH
     CQTQIHGKVS WDSSSSQQGS VDLKQDSVSP TTEEKNGIIV IRSTDRAIFS DHTDSRTTSG
     SSWSSPTLLC HSIAGKQGSF PGPSPALLGL KSKVEACEAK GGSQEARESN PREEVAPAKE
     RSFMSWFSSG PPVHNIKDNK DVFQKSEKNE DQEEDQIIEV DGWCHLPQIP LKSSPTDKAL
     QNCWGLPEAE VRVWGAQILL ALESLHQQGI LCRDLNPRNV LLTSNGKVCL TFFGQWSEVQ
     SEICCRAMDQ MYCAPEIGGV TRITEACDWW SLGTLLFELL TGMPLWQLHP AGIHTHTQLL
     IPDHLSTAAA SLLTELLQFD PGYRLGSGGG GVCDIKCHPF FSSVSWKALG C
//