ID   H2UZ00_TAKRU            Unreviewed;       282 AA.
AC   H2UZ00;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=HscB mitochondrial iron-sulfur cluster cochaperone {ECO:0000313|Ensembl:ENSTRUP00000042179.3};
GN   Name=hscb {ECO:0000313|Ensembl:ENSTRUP00000042179.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000042179.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000042179.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000042179.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the HscB family.
CC       {ECO:0000256|ARBA:ARBA00010476}.
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DR   AlphaFoldDB; H2UZ00; -.
DR   STRING; 31033.ENSTRUP00000074739; -.
DR   Ensembl; ENSTRUT00000042323.3; ENSTRUP00000042179.3; ENSTRUG00000016503.3.
DR   eggNOG; KOG3192; Eukaryota.
DR   GeneTree; ENSGT00390000008206; -.
DR   HOGENOM; CLU_068529_0_2_1; -.
DR   OrthoDB; 5473494at2759; -.
DR   TreeFam; TF319992; -.
DR   Proteomes; UP000005226; Chromosome 21.
DR   GO; GO:0001671; F:ATPase activator activity; IEA:InterPro.
DR   GO; GO:0051087; F:protein-folding chaperone binding; IEA:InterPro.
DR   GO; GO:0044571; P:[2Fe-2S] cluster assembly; IEA:InterPro.
DR   GO; GO:0051259; P:protein complex oligomerization; IEA:InterPro.
DR   Gene3D; 1.10.287.110; DnaJ domain; 1.
DR   Gene3D; 1.20.1280.20; HscB, C-terminal domain; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR004640; HscB.
DR   InterPro; IPR036386; HscB_C_sf.
DR   InterPro; IPR009073; HscB_oligo_C.
DR   InterPro; IPR036869; J_dom_sf.
DR   NCBIfam; TIGR00714; hscB; 1.
DR   PANTHER; PTHR14021; IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB; 1.
DR   PANTHER; PTHR14021:SF15; IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB; 1.
DR   Pfam; PF07743; HSCB_C; 1.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; Chaperone J-domain; 1.
DR   SUPFAM; SSF47144; HSC20 (HSCB), C-terminal oligomerisation domain; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   3: Inferred from homology;
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   DOMAIN          118..190
FT                   /note="J"
FT                   /evidence="ECO:0000259|PROSITE:PS50076"
SQ   SEQUENCE   282 AA;  32296 MW;  3B5B474CB1696E30 CRC64;
     MLSSNTWRTL CSRRALLSPN RMLMNRKAGQ ATVRFSVNTK SLNDVSFAKQ DSWRNNTIRK
     ALGNEKKRIF SAHVVFLRNY STSHIKLNCW KCKQPLENDP AFFCLACKVV QPPEEGTSYF
     KIMDCDYSFS LDTLKLQRRY VQLQRSLHPD NFSQKSVEEQ KYSEIQSALV NKAYKTLLKP
     LSRGLYMLEL QGMRIEEGTD SEADSQFLME LMEINEFLNE AQTAGEAEQI GGDVKGKLTD
     LTKRIDAALL KGDLAAAKAL LAQMKYYANI EEKVKQKLSE FM
//