ID H2V4A3_TAKRU Unreviewed; 772 AA.
AC H2V4A3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=RNA binding motif protein 26 {ECO:0000313|Ensembl:ENSTRUP00000044037.3};
GN Name=RBM26 {ECO:0000313|Ensembl:ENSTRUP00000044037.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000044037.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000044037.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000044037.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2V4A3; -.
DR STRING; 31033.ENSTRUP00000087805; -.
DR Ensembl; ENSTRUT00000044185.3; ENSTRUP00000044037.3; ENSTRUG00000017189.3.
DR GeneTree; ENSGT00510000046929; -.
DR Proteomes; UP000005226; Chromosome 13.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045137; RBM26/27.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR14398; RNA RECOGNITION RRM/RNP DOMAIN; 1.
DR PANTHER; PTHR14398:SF2; RNA-BINDING PROTEIN 26; 1.
DR Pfam; PF14605; Nup35_RRM_2; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 2.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 108..136
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 353..427
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT ZN_FING 108..136
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 654..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 514..555
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..216
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..334
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 86111 MW; 527C8A7240E969FD CRC64;
MRERDRERER ERDNSRSHSQ SRTRSRSRER ESGKLKYEQD QRAESSDGYT PAPLVSTATT
SHFPVPTLSS TITVVAPTHH HNNTSESWSD FHPDHPVDHV PFVRAPPPQQ RKRCRDYDEK
GLCMRGDMCP FDHGSDPVVV EDVNLPNIMS FQPPPQIPGV EPPPPPGLPP PPPPPLMNAP
PVNLRPPVPP PCALPPSLPP VQGPPPPLPP LQPSGMDAPP NSITSTVPTI VTSGIRCSLP
HASLPMFSSD TYDNDGYNPE APSITNTSRP LYRHRVNAQR PNLIGLTMGD VDQPQRGKIP
NNSMRIVMES DSRKRLPPHD GGIPIKKPRF DKPNFNKPNH QGYHKRLPFS LNTKLLVRQI
PPLLNNISKL NEHFSKFGTI VNLQVAYQND GEAALIQFAS PDEARRAIQS TEAVLNNRFI
SVHWFRDNGN DGQELLRSDV QSVKDRLGPL LTILFSFFLK NSLLQNPSKT SVKERLGFST
KPAAPVEKVF SSSMGLTKTV YNPAAITAAQ NSSEEALKKK LEALKLQQDV KKKKQEILEK
NIETQKLLLS KLEKNKGMKA EDKAKCMKTL SMLIKSISKL QDEIKGVSSS NSQQRTAKSK
AQAQKELLDA ELDLYKKSQA GEDTAMLKLQ YTQLQIEAAK RGILAPGRGR GLFTRGRGSA
RGRASRGRGR GAPVHAVVDH RPRALQISGF VDSDRVDLLP HFAQFGEIED CQIDENNLSA
VVTYKSRAEA EQIVFLSTSF TFQYQEESLS DDALLQDDDE EEDDNEPRSW RR
//
