ID H2XP99_CIOIN Unreviewed; 365 AA.
AC H2XP99; A0A1W2W783;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=LOC100175427 {ECO:0000313|Ensembl:ENSCINP00000031482.1};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000031482.1, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000031482.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WSCD family.
CC {ECO:0000256|ARBA:ARBA00010236}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|RuleBase:RU361155}.
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DR EMBL; EAAA01002801; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_002123122.1; XM_002123086.4.
DR AlphaFoldDB; H2XP99; -.
DR STRING; 7719.ENSCINP00000031482; -.
DR Ensembl; ENSCINT00000036638.1; ENSCINP00000031482.1; ENSCING00000025156.1.
DR GeneID; 100175427; -.
DR KEGG; cin:100175427; -.
DR GeneTree; ENSGT00940000169474; -.
DR HOGENOM; CLU_758536_0_0_1; -.
DR InParanoid; H2XP99; -.
DR OMA; RCHITAY; -.
DR OrthoDB; 3971278at2759; -.
DR Proteomes; UP000008144; Chromosome 9.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR45964:SF5; WSC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45964; WSCD FAMILY MEMBER CG9164; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Transferase {ECO:0000256|RuleBase:RU361155}.
FT DOMAIN 197..291
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 365 AA; 42340 MW; 6F479F97AC0A0893 CRC64;
MMRTTKQTVL LGFGLFVVSF LTILSRRHDF WKISNQRMYL PHADRHRVPH YRTHVQNIEQ
NSIKEEPKWM TIIREQQATK KRFRATMKLN TSEIWTNNKP TKDCNDTRFL NKLLINKPGK
FNRRVALASF PGSGNTWLRH LFHVTTGIWT GSVYFDAKLY SGGFPGEVSD CRDPSVFAVK
VHDAMHSDVM ECYFDDIILV LRNPYNSIMS EFNRRKGASH VAVADEKEFL TSDWERYAKM
KINSFNAVLQ RWLELCSQKS SKHRCHITAY QDLVQNTTAE MAKILKHLGL PSHRLRCLDI
PGFKDGPFHR KGTKTTNKTN RTQPLCLLTQ GTQDLLSRVV ANGKEKLLRG GREFAKELEY
QMPTC
//
