ID   H2Y781_CIOSA            Unreviewed;      1270 AA.
AC   H2Y781;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=Cilia- and flagella-associated protein 61 N-terminal domain-containing protein {ECO:0000259|Pfam:PF16092};
OS   Ciona savignyi (Pacific transparent sea squirt).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC   Cionidae; Ciona.
OX   NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000001179.1, ECO:0000313|Proteomes:UP000007875};
RN   [1] {ECO:0000313|Proteomes:UP000007875}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., Ait-zahra M.,
RA   Allen N., Allen T., An P., Anderson M., Anderson S., Arachchi H.,
RA   Armbruster J., Bachantsang P., Baldwin J., Barry A., Bayul T.,
RA   Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., Borowsky M.,
RA   Boukhgalter B., Brunache A., Butler J., Calixte N., Calvo S., Camarata J.,
RA   Campo K., Chang J., Cheshatsang Y., Citroen M., Collymore A., Considine T.,
RA   Cook A., Cooke P., Corum B., Cuomo C., David R., Dawoe T., Degray S.,
RA   Dodge S., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A.,
RA   Elkins T., Engels R., Erickson J., Farina A., Faro S., Ferreira P.,
RA   Fischer H., Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G.,
RA   Gnerre S., Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K.,
RA   Hafez N., Hagopian D., Hagos B., Hall J., Hatcher B., Heller A.,
RA   Higgins H., Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E.,
RA   Iliev I., Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M.,
RA   Karlsson E., Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E.,
RA   Labutti K., Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA   Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., Lui A.,
RA   Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., Manning J.,
RA   Marabella R., Maru K., Matthews C., Mauceli E., Mccarthy M., Mcdonough S.,
RA   Mcghee T., Meldrim J., Meneus L., Mesirov J., Mihalev A., Mihova T.,
RA   Mikkelsen T., Mlenga V., Moru K., Mozes J., Mulrain L., Munson G.,
RA   Naylor J., Newes C., Nguyen C., Nguyen N., Nguyen T., Nicol R., Nielsen C.,
RA   Nizzari M., Norbu C., Norbu N., O'donnell P., Okoawo O., O'leary S.,
RA   Omotosho B., O'neill K., Osman S., Parker S., Perrin D., Phunkhang P.,
RA   Piqani B., Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V.,
RA   Raymond C., Retta R., Richardson S., Rise C., Rodriguez J., Rogers J.,
RA   Rogov P., Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA   Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA   Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., Stetson K.,
RA   Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., Tenzing P.,
RA   Tesfaye S., Theodore J., Thoulutsang Y., Topham K., Towey S., Tsamla T.,
RA   Tsomo N., Vallee D., Vassiliev H., Venkataraman V., Vinson J., Vo A.,
RA   Wade C., Wang S., Wangchuk T., Wangdi T., Whittaker C., Wilkinson J.,
RA   Wu Y., Wyman D., Yadav S., Yang S., Yang X., Yeager S., Yee E., Young G.,
RA   Zainoun J., Zembeck L., Zimmer A., Zody M., Lander E.;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAVP00000001179.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; H2Y781; -.
DR   STRING; 51511.ENSCSAVP00000001179; -.
DR   Ensembl; ENSCSAVT00000001192.1; ENSCSAVP00000001179.1; ENSCSAVG00000000662.1.
DR   eggNOG; ENOG502QSEC; Eukaryota.
DR   GeneTree; ENSGT00390000004987; -.
DR   HOGENOM; CLU_003251_0_0_1; -.
DR   InParanoid; H2Y781; -.
DR   OMA; RWNEGQI; -.
DR   TreeFam; TF323897; -.
DR   Proteomes; UP000007875; Unassembled WGS sequence.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR038884; CFAP61.
DR   InterPro; IPR032151; CFAP61_N.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR21178; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61; 1.
DR   PANTHER; PTHR21178:SF8; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61; 1.
DR   Pfam; PF16092; CFAP61_N; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 2.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007875}.
FT   DOMAIN          16..269
FT                   /note="Cilia- and flagella-associated protein 61 N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16092"
FT   REGION          307..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1036..1060
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..347
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1270 AA;  141885 MW;  846F0D18C7CFA41C CRC64;
     LTYVFTLKHV PQVINARRTE SLDAPAILEL VAPRTTSQFG RVNIVHLIEK SNLSVTLSNE
     QNEVLGFAGF LDQPQLEVCN PADWECWLSD MHYKVAANAT PLNSLFLHHF VAKDDYTIGC
     ASEIVRTVFN AVPELRFIFL TLRSDNNPEP ALAQIFQPAE RDGLGGYCHY TLYVCHRHNH
     APLLHIRRAC VEDHDDLTPL FKRLNNNLIE TYGNYFLAEM IEAQNDDNQA LVAEVEGKAV
     GFMSVSSHVN VGLLQDCFEL SSFHGLCKPH PDDVLVEDAP STPPASTPIV PASTPIVPAS
     TPIVPASTPI VPAQPERKES EVSMGKNSSE AIDQGIGSTS SDPSMTTLLP SSGMKPKLSE
     FHMGSRSSLP GGPDVFTSTS PTGFSVSMGA SSCEPDAFSI QLFCMEEQFE MRSADFLPKI
     FKLFPKKDFA VITVPHLVPE FPLIQQFVRV TPKRTSNVPH ELYVFHRNGL LSAGFSVRPA
     KTDDYEQVVK LTRNINLHEN LLADLRSYNS ARRDEDGTEI QAFVADCVGQ VVGICIMRRE
     ENIEEVRAHY NVEDFIYFNH HRRDEHAHLH HFALNPIFQH YSKHFIKEVL RQGHKSCLYY
     PIYPTTAPTN VSASHSLITG LNFMVPVRAR RQIDYPLQEL GVNAPSERVI SHSPPYAINH
     INRKLTLEPK VTINARIVVV GASDVGISFL ETLCFCPHLR FNNLTLVSKR GLPHKLFSPS
     QTYSSEDLAR LSLRSWVNNP ISTGFMSDID RNSKHVITAD GARVAYDHLV ICTGQQYQIP
     CPTGADVHNM ATNYDLTKGA ANQPYDITKP IPDNVMAVND SYDITKLSMW ASNSPSIIIY
     GRSFEAYHIT QCLLSWGIPG ARVILVRPPA QNSGVSVSDD NTNGDPFNEP LVSKAVELGL
     QESGVRILAN HVLAAWGEEG NTHGGSTITS VSFTTPTKPL SLPCMGFISL HPKRIDIRTF
     LALNRACLVF DGRLTIDASF KTNDPSIWAA GPITKYARRY HADGYWARHE NYSSKEIGFR
     LAMTILPLFD PTLDGADPGD YPPTTPATTM RGESRQENPH EKLIPVYMEP KVTMGELPGG
     FTYLHVRKPG ERAPYAAQLD SIDHGAEVVT GSPENGNYFR LHLNRFDRVE TITCLVRGSH
     LSTSNLIRLY GTHERYLNNL VGRNKEGMLV DLFAFFRAPW SMAIYHDRFP DFRQEIRDLL
     STSLGANVPS VEAKVRQLVD EDLFINNQQR ETLRKYYSQT GQRKAVEGRL LSFLSYNYYH
     LPMFAKPGMV
//