GenomeNet

Database: UniProt
Entry: H2Y876_CIOSA
LinkDB: H2Y876_CIOSA
Original site: H2Y876_CIOSA 
ID   H2Y876_CIOSA            Unreviewed;      5004 AA.
AC   H2Y876;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   10-MAY-2017, entry version 32.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000001524};
OS   Ciona savignyi (Pacific transparent sea squirt).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000001524, ECO:0000313|Proteomes:UP000007875};
RN   [1] {ECO:0000313|Ensembl:ENSCSAVP00000001524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E.,
RA   Ait-zahra M., Allen N., Allen T., An P., Anderson M., Anderson S.,
RA   Arachchi H., Armbruster J., Bachantsang P., Baldwin J., Barry A.,
RA   Bayul T., Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L.,
RA   Borowsky M., Boukhgalter B., Brunache A., Butler J., Calixte N.,
RA   Calvo S., Camarata J., Campo K., Chang J., Cheshatsang Y., Citroen M.,
RA   Collymore A., Considine T., Cook A., Cooke P., Corum B., Cuomo C.,
RA   David R., Dawoe T., Degray S., Dodge S., Dooley K., Dorje P.,
RA   Dorjee K., Dorris L., Duffey N., Dupes A., Elkins T., Engels R.,
RA   Erickson J., Farina A., Faro S., Ferreira P., Fischer H.,
RA   Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G., Gnerre S.,
RA   Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N.,
RA   Hagopian D., Hagos B., Hall J., Hatcher B., Heller A., Higgins H.,
RA   Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E., Iliev I.,
RA   Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M., Karlsson E.,
RA   Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E., Labutti K.,
RA   Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA   Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O.,
RA   Lui A., Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J.,
RA   Manning J., Marabella R., Maru K., Matthews C., Mauceli E.,
RA   Mccarthy M., Mcdonough S., Mcghee T., Meldrim J., Meneus L.,
RA   Mesirov J., Mihalev A., Mihova T., Mikkelsen T., Mlenga V., Moru K.,
RA   Mozes J., Mulrain L., Munson G., Naylor J., Newes C., Nguyen C.,
RA   Nguyen N., Nguyen T., Nicol R., Nielsen C., Nizzari M., Norbu C.,
RA   Norbu N., O'donnell P., Okoawo O., O'leary S., Omotosho B.,
RA   O'neill K., Osman S., Parker S., Perrin D., Phunkhang P., Piqani B.,
RA   Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V., Raymond C.,
RA   Retta R., Richardson S., Rise C., Rodriguez J., Rogers J., Rogov P.,
RA   Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA   Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA   Spencer B., Stalker J., Stange-thomann N., Stavropoulos S.,
RA   Stetson K., Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P.,
RA   Tenzing P., Tesfaye S., Theodore J., Thoulutsang Y., Topham K.,
RA   Towey S., Tsamla T., Tsomo N., Vallee D., Vassiliev H.,
RA   Venkataraman V., Vinson J., Vo A., Wade C., Wang S., Wangchuk T.,
RA   Wangdi T., Whittaker C., Wilkinson J., Wu Y., Wyman D., Yadav S.,
RA   Yang S., Yang X., Yeager S., Yee E., Young G., Zainoun J., Zembeck L.,
RA   Zimmer A., Zody M., Lander E.;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAVP00000001524}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCSAVP00000001524}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   Ensembl; ENSCSAVT00000001544; ENSCSAVP00000001524; ENSCSAVG00000000873.
DR   GeneTree; ENSGT00760000119152; -.
DR   Proteomes; UP000007875; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007875};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4357   4376       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4556   4576       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4616   4635       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4745   4764       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4807   4827       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4881   4904       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       96    151       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      158    204       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      212    267       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      273    323       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      338    395       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      587    802       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1021   1216       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   5004 AA;  566159 MW;  6ACAC47BAFFCD382 CRC64;
     SDVTMDGDGD EEVHFLRTED EIYLQCVTQK DHQGKLCLAA EGFGNRLCYV EQSHEDKDSR
     PTDAPRCVFV LAQALSVRAL QELLAKDEVK DGSTHSRTLL YGNAVQLKHG LSAMYLTCLT
     TASSSCDKLA FDVGISEDQS GEASWWTVHP TSKQRSEGEK VRIGDDLILI SIASERYLHL
     SCGDPGGVNV EASFQHSMWT VAPIASGGSK VEGYLTGGDV IRLFHGHMDD CLTVDSAEEM
     KSHTRPIVYE SGRAGSHARS LWRLELLQIK WFGSHVAWGI PFRLRHITSG LYLSVMDDQS
     LGLTSPEGAT YRTAVFCWQA SKDRPESKAD HEIDGMGAPE IKYGDSVCYL QHVDSGLWMT
     YQTIDTKSGR CGPKQRMAVL HDDGRMDDGF MLSRAHPGEA RTATIIRRTT EIFCNFINAL
     DSHQNKKMSR RPEQPNVEEV EQCVDDLIEY FQEGRGEEGG HEVHQHIVQE LKNRQDLFQE
     EDAVSHVLQC IDKLAVYGDA GNFAQIVGVE ASASYESLLN SMYVLLAATV RGNRNNCSKF
     APHLDWLVGQ LDGQQAAMGR HVRLGILEVL AAVLEDSQEA LNMMKQDHIR SIISLLEKQC
     RNPKVLEVLS SLCVCNGVAV RGNQNLICET LLPGRDLLLQ TALQSYITNV QPNIYMGVSN
     ACAQYKKWYY EVIVEAVDRS TFAGHLRVGW ANTEGFSPYP VGGDYYGENG VGDDMHSFGF
     DGINLWTSHR ACPVGSNNRH ILAPNDIISC CMDLSIPTIS FRINGQPVQG MFEDFNLNGL
     FFPVVSFSPG VKVRFLFGGP HGEFRFLPPV GYAPAYEALL PGRRLFLSPC KTYGNLSRGH
     LMGPGSSWER TVFVPNAVNT QNVILSHYLQ NVVPKLESIH ELWAMNRIRG GWSYGTVRDE
     AKKQNPCLVE FARLPEQERS FNLTMSYETL RTIIALGYHV GIADEEAEHG LRKLKLPRSY
     IMASGYKPSP LDLSHVKLTN QMEDLVEKLA DNAHNVWARE RVKQGWTYGV NLDVGKKRNP
     RLVPFQLLDE LAKQSNRNSI RELVRTLIGH GYMIEPPDDR LKDKTTRIKN PVQNNKVRIF
     RAEKTHSVCA GKWYFEFTIE TQGVMKVGWV DPDCLPSVDL GSNHQAYVFD GVNVSMHVLN
     DGSETFGQRW KPGDVVGCLL DFSERKIFFS LNGELLVDRC GHETAFRNLP SDLTLVPAVS
     LSVDQRGTLN LGKDPDSFQF YSTVGQKEGY QPFAAGMRCG VAMWFTKNLP SFCNLDPVHG
     NIEVKRLSAS HHKPPRLKVM YKLIGGSRSH DHQEWVYTRL NLPVSTDAVF TKRLVLPQMR
     YTNLMFAQIS TAISRFCGRL REEASPPSPI MTSRTNVIII TSTPCPSQVT HHPNTPSPHI
     PLTPTQPPTP IPTPHTHPNA SVSRYMKVFR LKRCLTHTWS STPPVWGDQD NQRRPYLVNK
     VKPGLKGSKF HFSRTKTSNA HVGSNQANQS KPRLAEEVLP DHYNEVLYKN DIDQLMRSTQ
     YSFSVRIFPE QDLGSLYVGW VTSDFHWNVD NFQRGLIPTV TITLGDNKGK ISERYLRSNC
     FVLCCGDLPQ QAMPPNQSSP GIVVTCIIDT ATGLLTFAAN GSDLNTFFQV EPNVELYPAV
     IALPTAHNIF QYELGRTKHI MPLSAAVLKC ERKNVVPQCP PRLQVQTLEQ VSWTRMPGRL
     PRPECRRDMD RTKGWTSESK SSDSDAYNVV VVHIPEENRC IDLLELGENA DLLRFHERTL
     KLYSSMCALG NHRVAHALCS YIDEKQLMRI IRTEGLVGSV RAAYHDLLIE MHLSPHANAR
     RNTQHEYMFP LNDNTQSIGL FSDPASKRPM VPGVGPSSSI RPTLHWSPIN VVMHPSLIHD
     VPLEVPEFPL DELRQNVIGQ LHEAIRACYR KCKDSTGKNQ EYLLVPPLRL ALTLLTMGVF
     NDEDITKLLI LLAPSFIRTL VEDESLSDSH CGLLGLQLVE SVKLEACLLL EHLMELVLRH
     RVEALVSFSC VIVEELQQDQ KSRYQGVMEA INMSAAMTAK MTREFRSPPL EQMAILLKFK
     SEELEENCPL PQHIKDLLWN FHTDMLLDCG EQIEEEPVEE DNQDTLRSKL SSIVSRILHK
     RKEEEESPEE SSHATVGGGS FRDLIISTMM GWARGPSINN PQLVRAIFRL LYRQYNGVGE
     MQNALMKTYC ISAASEGDTM ALLESLSRLR SLLSVQLGQD EETLIIKGLN SIMNNKVFYQ
     HPNLMRILCM HETVMEVMVS VLDGDGDSDS IEVKFPRMVA ACCRFLCYFC RISRLNQGAM
     FEHLGFLLEH SSVGLATPSM RGSTPLDVAA ASVMDNNELA LALKESDLAK VNLALATCGV
     ESSQLLLRKG YPDIGWNPVE GERYLDFLKN AVFVNGESVE ENANLVVRQL IRQTECLGPS
     LRGEGGHGLL AAITSALQIC RDRSRDGPDL NLCNEYDNDD DIHMGFSILA FYSTLIDLLG
     RCAPEKYLIM QGKSDAIRIR SILRSLVPRE DLIGVISLPF DLPRFERGST NIREPDLSAC
     FIPDHKASMV LFLERVYGID SPHLLLRLLE SGLLPDMKSA AQLDVPHINS TDMALALNRY
     MCHSVLPLLV KHVSLLAHCQ HRPQLLDQLL HTIYRMSQAQ ALTKAQKEMI SECLVAVASV
     LQPSLLQGLL RKLTFDVPAL TEETYIPLQL LKEHYSRCWK YYYLLEGCPD FGVATDEEKH
     ITMVLFWGIF DSLVKKPYSQ ELFSKVLPCL CSIGNALPPD YALSPALEKL HQQSSIDSHG
     KFHPQPVDTK SILFPEKLDV FVNKCSEQWH DTWALERFTL GWSYEAHYNE ALKQHPMLKP
     YRLLNDREKD VYRPSVREGI KALIAWGWSF KKIVEATDIS QLPAKVRCSS QSNIVISSDA
     HGYLPRPYDL SGVSLGREMM RTAEMLAENF HLVWARKKMG ELESKHTNLP SHPMLVPYDR
     LTAKEKERDR GKAYDLLKFF QVDNLSPIKA EKEEVDVKSS VEKRFSSMVL QRLLSYQEHA
     AFGGNYEPPS LQQPQANDDI KFFAKVAMPL MESYFKNQEI YYVEACGNAN DGIACRKPNA
     FILSRLFCKM ALLIRQRITM FGVDAGTAIN CVKILAECID ASTITKACSE SMKQALISFF
     NNAADDLKLM LNHIRSGRIK ILQTMVAGAH TSNYVSHCLL PLLTILFRHL GRHNFGGELL
     LDEIQVSCYK ILNGLYSLGT GKSAFIDRKY LNIPYRAKSQ VGECLAAFAS AFPVSFLEPK
     LNKFNSYSIY NILSIKDRKA LGLPPNLEQL TPHLPILETL LADINHLADS GAKYEEAPEM
     IDIILPLICS YLPPWLKQGP DDNSAVSTGF SSSVSSKVLD VVLRDVLRLI HNNLGTDEAD
     WMRRIAVYTQ PIMVRSDPDL LADHFLPMII KLSKRIEQAR DLEEQVKYDQ RVNDVSDLEL
     LMLEDYGIIS RDLYAFYPLM VRYIDLSKSC WIRERNPIAL QLFRIISKIM IIWSKSINFR
     REEQNFVVQN EIDNMSVLTA DKSATPSAAS MLVSMISMLV SASQRVVKRR GDRYSPSTSL
     VVACLKRMMP VAINTGHVAD FQLLQEAKSR FVQRDTEDDI REYLVQVLNV SCLSFQEVSD
     TTWRPQLNCF VRLHSFMSFQ SEGTSTNESQ DKVESRADWL LEIARAQHYL FMVDHPPKSR
     RAVWKKLMSK QRKRAVVSCF RMVPLYNLPK HRVSNCFLSN YMEKWLNSED QDKCGLIEII
     TPSVEGESGG SDPLQQLISV FSISAITSLI HRAIEDDDLY LSYAELMAES CHTGDDDDEE
     EEKSFEVSEG VYVSLQEKEK EKQRLLYEQK RLATRGVAEM VLYMISASGG EVSDTVLSTL
     QLGIALLTGG NVLVQKTMLA HLQAKKDVRF FTSLAGLMQQ CSVLDLNAYE RCLKSESLGH
     ASEGTVTGGE TMGDAELTCA LFRFLQLLCE GHNGDFQNYL RSQVGNNTTV NIIISTVDYL
     LRLQEAITDF YWYYSAKDTI DAPGRENFSK AIEVAKQVFN SLTEYIQGPC EGNQQALAHS
     RLWDAVVGFL HVFAHMQMKL AQDSTRQLSL LKELLDLQQD MIVMLLSMLE GNVVNGTIGK
     QLVDTLIESS HNVGLILKFF NMFLRLKDIT ESEKFTEYDP EHNGVVSRRD FHKAMEASKV
     YSREEIDFLL RCAVTTDDDK LNYMDFTEQF HGPAADIGFN MAVLLTNLSE HMPHDTRLGK
     FLEMAEAMLE YFQPNLGRIE IVGGARRIER VYFNIRPSSL EQWQKPQVQE SKRQFFFDVI
     NDEGEGGRME EFVNFCEDTI FEVGGWTSSI PGNLFRVMEL FNYLNKRLVD IYLRDNPSPS
     QITLVVSYNL YLNFLCNLHH KSARPGSEAA PLDQPTMMLM MKILMFIVFF SNKLVVALKS
     KRVSEVVGEM PSPTQHGVED GVLDEDASDA SDPLKSDRDD LIVDVFGMDI KKGKELMKAV
     VHTKREAGFG DFSVEEAADT LSMIASDYDS GFNTPRATRI KKRRKLLRKG RRLDAQEAST
     LSRTMSFDMT TADDSSCTPW QSCMSACGRP ARYKQQEIET FKSTSHSQGL FARNFYNFKI
     LALIITFIIN FFLLFYKVSG CDKSYWQSIN EDLDVDESER LVLVDTTLYM EPALKIFRAI
     HFILSFSMLV SYYGLKVPLV IFKREKEIAR KLEFGGLYVS EDPSDDDLSG RWDRLVVSAP
     SFPSNYWDKF IKKKVLDKFG EQCGVERIRE LLGMSESSTS FVEDEEPIKG NIITQLLKVD
     LKYTIWKVGV VFCDQSFLYL LWYFTMSIFG QYNHFFFSLH LLDIAACSKG LRTILTSVTH
     NGKQLVLTIG LLTVVVYLYT VVAFNFFKKF YNKGENDEDD WKCNSMFTCF QFHFYSGVRA
     GGGIGDELDD PSGDAWEFYR IAFDISFFFF VIVILLAIIQ GLIIDAFGEL RDQQEQVKED
     MDTKCFICTI GIDYFDQVPH GFESHTMQEH NLANYMFFLM HLINKDETEH TGQETYVWQQ
     YQERCWEFFP AGDCFRKQYE NELS
//
DBGET integrated database retrieval system