GenomeNet

Database: UniProt
Entry: H2YFM2_CIOSA
LinkDB: H2YFM2_CIOSA
Original site: H2YFM2_CIOSA 
ID   H2YFM2_CIOSA            Unreviewed;      1524 AA.
AC   H2YFM2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-SEP-2017, entry version 29.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000004120};
OS   Ciona savignyi (Pacific transparent sea squirt).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000004120, ECO:0000313|Proteomes:UP000007875};
RN   [1] {ECO:0000313|Ensembl:ENSCSAVP00000004120}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E.,
RA   Ait-zahra M., Allen N., Allen T., An P., Anderson M., Anderson S.,
RA   Arachchi H., Armbruster J., Bachantsang P., Baldwin J., Barry A.,
RA   Bayul T., Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L.,
RA   Borowsky M., Boukhgalter B., Brunache A., Butler J., Calixte N.,
RA   Calvo S., Camarata J., Campo K., Chang J., Cheshatsang Y., Citroen M.,
RA   Collymore A., Considine T., Cook A., Cooke P., Corum B., Cuomo C.,
RA   David R., Dawoe T., Degray S., Dodge S., Dooley K., Dorje P.,
RA   Dorjee K., Dorris L., Duffey N., Dupes A., Elkins T., Engels R.,
RA   Erickson J., Farina A., Faro S., Ferreira P., Fischer H.,
RA   Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G., Gnerre S.,
RA   Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N.,
RA   Hagopian D., Hagos B., Hall J., Hatcher B., Heller A., Higgins H.,
RA   Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E., Iliev I.,
RA   Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M., Karlsson E.,
RA   Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E., Labutti K.,
RA   Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA   Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O.,
RA   Lui A., Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J.,
RA   Manning J., Marabella R., Maru K., Matthews C., Mauceli E.,
RA   Mccarthy M., Mcdonough S., Mcghee T., Meldrim J., Meneus L.,
RA   Mesirov J., Mihalev A., Mihova T., Mikkelsen T., Mlenga V., Moru K.,
RA   Mozes J., Mulrain L., Munson G., Naylor J., Newes C., Nguyen C.,
RA   Nguyen N., Nguyen T., Nicol R., Nielsen C., Nizzari M., Norbu C.,
RA   Norbu N., O'donnell P., Okoawo O., O'leary S., Omotosho B.,
RA   O'neill K., Osman S., Parker S., Perrin D., Phunkhang P., Piqani B.,
RA   Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V., Raymond C.,
RA   Retta R., Richardson S., Rise C., Rodriguez J., Rogers J., Rogov P.,
RA   Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA   Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA   Spencer B., Stalker J., Stange-thomann N., Stavropoulos S.,
RA   Stetson K., Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P.,
RA   Tenzing P., Tesfaye S., Theodore J., Thoulutsang Y., Topham K.,
RA   Towey S., Tsamla T., Tsomo N., Vallee D., Vassiliev H.,
RA   Venkataraman V., Vinson J., Vo A., Wade C., Wang S., Wangchuk T.,
RA   Wangdi T., Whittaker C., Wilkinson J., Wu Y., Wyman D., Yadav S.,
RA   Yang S., Yang X., Yeager S., Yee E., Young G., Zainoun J., Zembeck L.,
RA   Zimmer A., Zody M., Lander E.;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAVP00000004120}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC   -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit
CC       (TC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCSAVP00000004120}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   Ensembl; ENSCSAVT00000004182; ENSCSAVP00000004120; ENSCSAVG00000002422.
DR   GeneTree; ENSGT00830000128242; -.
DR   Proteomes; UP000007875; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IEA:InterPro.
DR   GO; GO:0070509; P:calcium ion import; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR030160; VDCC_T_a1H.
DR   InterPro; IPR002077; VDCCAlpha1.
DR   PANTHER; PTHR10037:SF227; PTHR10037:SF227; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR00167; CACHANNEL.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|RuleBase:RU003808};
KW   Calcium channel {ECO:0000256|RuleBase:RU003808};
KW   Calcium transport {ECO:0000256|RuleBase:RU003808};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007875};
KW   Ion channel {ECO:0000256|RuleBase:RU003808};
KW   Ion transport {ECO:0000256|RuleBase:RU003808};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003808};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003808}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26   1524       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003578052.
FT   TRANSMEM     45     64       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    133    156       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    278    300       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    306    331       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    500    518       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    533    555       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    624    650       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    698    721       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    962    983       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    995   1014       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1059   1081       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1162   1185       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1275   1296       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1308   1329       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1341   1359       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1412   1432       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1501   1523       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    343       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      499    726       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      922   1132       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1273   1523       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1524 AA;  174191 MW;  7381DDC9DEFE3F5A CRC64;
     WFERVSMLVI LLNCVPLGLY QPCQPKPGLP CGSPRCSILE ICDHFVFAFF AIEMLIKMLA
     MGVWGKLGYL GEAWNRLDFF IVLCGMMEYT LQLEDTMNFT SVRTVRVLRP LRAINRVPNM
     RILVMLLLDT LPMLGNVLML CSFVFFIFGV VAVQLWEGTL RQRCFLDPNI NLGNPLTPIF
     HSSLEIAPFY SRGEEDLAIC SLPMDSGEFH CSDRSIITPF TVENITCSLN VTHYQVGKPV
     NHLYTGTPMC IDWNQYMNTC KAGDSNPSLG SINFDNIMYA WVAIFQVISL EGWVDIMYYL
     MDGYSFYSFI YFILLIVIGS FFMINLCLVV IATQFSETKQ REQRLMEEQR LRFKSNDSTL
     ASYSPPGNCY EEMLKYISHL YRKNKRKIKS NIICAMLYTY VSFQRRWHKW QTEKKLKRSG
     MGSLKREVPV RSVRKKKKSI HLHHHHHHHH HHYHIADTID RTGDGASVDQ QLQGSTAEKE
     RFSFLRDFQE QTKRVVDSSY FNRGIMIAIL INTLSMGIEH HSQPDGLTEV LEISNVIFTT
     LFALEMIAKI VAFGVAGYTK NLYNVFDALI VIIRFVLRTQ NSGGGLSVLR TFRLLRVLKL
     VRFMPALQRQ LVVLMKTMDN VATFMMLLTL FIFIFSILGM HLFGCDFCWV NQYGRTECDR
     KNFDSLLWAF VTVFQILTQE DWNIVLYNGM AATSPFASIY FITLMTIGNY VLFSLLVAIL
     VEGFQAEDGD DEVDDYVETS SDEDEEVELL TRGRCPLIKV STSKVFKHGF IPLDELSVRF
     SLSNHPSDTL RLLCRHFIFS HKNQEKESEN WSLPVITRTS ATPLHTPTLA NISQENSLEK
     SFLSAESRGS STDSQTEKDA NHNTPQSVKK HAILSRKPST EVRLFAVMLG PPNWTYTRKE
     WSLYLFSPEL KFRRAVQKIT EHKVFDNTIL LLIFGNCITI AMERPSLKEG DYEREVLDCF
     NNIFTFVFLL ELILKVIASG FYVGPKAYLK SGWNVLDFFL VSTSLIDFIM TLAYSSGSKL
     LGMLRVFRLL RALRPLRVIS RAPGLKLVVQ TLISSLKPIG NIVLICCAFF IIFGILGVQV
     LKGKFYRCVG PDLRNVTNKS NCLANPNNNW VNRSRYFRTN GQYLSSKYEG VCSNKCWLAT
     NHWGATDLNT SIVAVASSTE QWLLVLLVLL VLLSGFFNDI HYVVILQIKT KIQNIQEYRR
     RKQERLDYKK SMRHARGEQR LNFRRKTLSR AKNQVTGFRG HCFSNSLSSF ADNTKYYEEY
     GPARRALHDV CMNKYFEIGI SIVIGINILT MAAEHYKQPK VLDQALKIAN YFFTAVFILE
     AVLKLIALGF RRYFRDRWNQ VDMLIVILSV VGIAVEALMT SGDERSLLIN PTIIRVMRVL
     RIARVLKLLK VSKGIRSLLE TVGNALPQVG NLGLLFLLLF FIFAALGVEL FGTLSCDEAH
     PCNGLSRHAS FSNFGIALLT LFRISTGDNW NGIMKDTIRQ ECDASDSCMV NCCSSSIISP
     IYFVLFVMTA QFVLVNVVVA VLMK
//
DBGET integrated database retrieval system