ID H2YI75_CIOSA Unreviewed; 1881 AA.
AC H2YI75;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Laminin G domain-containing protein {ECO:0000259|PROSITE:PS50025};
OS Ciona savignyi (Pacific transparent sea squirt).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000005024.1, ECO:0000313|Proteomes:UP000007875};
RN [1] {ECO:0000313|Proteomes:UP000007875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., Ait-zahra M.,
RA Allen N., Allen T., An P., Anderson M., Anderson S., Arachchi H.,
RA Armbruster J., Bachantsang P., Baldwin J., Barry A., Bayul T.,
RA Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., Borowsky M.,
RA Boukhgalter B., Brunache A., Butler J., Calixte N., Calvo S., Camarata J.,
RA Campo K., Chang J., Cheshatsang Y., Citroen M., Collymore A., Considine T.,
RA Cook A., Cooke P., Corum B., Cuomo C., David R., Dawoe T., Degray S.,
RA Dodge S., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A.,
RA Elkins T., Engels R., Erickson J., Farina A., Faro S., Ferreira P.,
RA Fischer H., Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G.,
RA Gnerre S., Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K.,
RA Hafez N., Hagopian D., Hagos B., Hall J., Hatcher B., Heller A.,
RA Higgins H., Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E.,
RA Iliev I., Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M.,
RA Karlsson E., Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E.,
RA Labutti K., Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., Lui A.,
RA Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., Manning J.,
RA Marabella R., Maru K., Matthews C., Mauceli E., Mccarthy M., Mcdonough S.,
RA Mcghee T., Meldrim J., Meneus L., Mesirov J., Mihalev A., Mihova T.,
RA Mikkelsen T., Mlenga V., Moru K., Mozes J., Mulrain L., Munson G.,
RA Naylor J., Newes C., Nguyen C., Nguyen N., Nguyen T., Nicol R., Nielsen C.,
RA Nizzari M., Norbu C., Norbu N., O'donnell P., Okoawo O., O'leary S.,
RA Omotosho B., O'neill K., Osman S., Parker S., Perrin D., Phunkhang P.,
RA Piqani B., Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V.,
RA Raymond C., Retta R., Richardson S., Rise C., Rodriguez J., Rogers J.,
RA Rogov P., Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., Stetson K.,
RA Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., Tenzing P.,
RA Tesfaye S., Theodore J., Thoulutsang Y., Topham K., Towey S., Tsamla T.,
RA Tsomo N., Vallee D., Vassiliev H., Venkataraman V., Vinson J., Vo A.,
RA Wade C., Wang S., Wangchuk T., Wangdi T., Whittaker C., Wilkinson J.,
RA Wu Y., Wyman D., Yadav S., Yang S., Yang X., Yeager S., Yee E., Young G.,
RA Zainoun J., Zembeck L., Zimmer A., Zody M., Lander E.;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAVP00000005024.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR STRING; 51511.ENSCSAVP00000005024; -.
DR Ensembl; ENSCSAVT00000005095.1; ENSCSAVP00000005024.1; ENSCSAVG00000002999.1.
DR eggNOG; KOG3597; Eukaryota.
DR GeneTree; ENSGT00940000154091; -.
DR HOGENOM; CLU_000473_1_0_1; -.
DR InParanoid; H2YI75; -.
DR OMA; QCKVIPL; -.
DR TreeFam; TF316876; -.
DR Proteomes; UP000007875; Unassembled WGS sequence.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR45739:SF12; CHONDROITIN SULFATE PROTEOGLYCAN 4-LIKE ISOFORM X2; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 9.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR PROSITE; PS51854; CSPG; 10.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1881
FT /note="Laminin G domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005683239"
FT DOMAIN 28..197
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 207..373
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REPEAT 544..635
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 654..759
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 893..983
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1115..1204
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1226..1323
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1340..1431
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1455..1544
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1559..1659
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1678..1774
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1799..1881
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
SQ SEQUENCE 1881 AA; 208798 MW; 18AC5C99893C864B CRC64;
MKLLNAVHLV VGYTLFMLVS RSCSSSYSAS FYGNSFLFER LSDNSADTTL SLQFQTRALD
GIILIAAGQR DYLIVSLKHG RLEIRINTGY GEEVLKTTSK EKYNNLLWHE VQLIRHAHNV
WVDVNKKNII TSTLQAGNRE YNLNIDLGVF LGGFDRNVGS SYVGKLEQFF RGCILSAVYN
DVDVLDPIMS NKHPLGCSNI FRAQPNQPMS FTSAESFLKL PTWPTSDDEA LFECRLRTLG
QDGLIMFSSG ATRSEFVMLE LSKGHIRGSI NRGSGVVALQ STTHVNDGGW HRNVGIIILH
EYLTWISNRP PSGDLDMTGG MYIGGMDRGL KQQMRSSGIQ TQSFPGCFKN LRVNRIRKTF
KDFTSTHLLN VGCPSNMTTL PHAQSSSQVV PNFVIVPHTQ PRTSHKPSST MVGQQRHVCF
QQIIHNIELM EGGRVDLSDE IIRFDLMSDE RRLRNDNSMQ FLTFNLTQPA LHGGLVMGGQ
GVVGGDALVM QDIHDGKLTY VHDGSETRTD RIVYTVGTTG LDASIRTKVM KYSLNITIIP
VDDPPVLSIP ANYTFTPIRN ARTPLPTHIL RSYDPDSDPS DIIYHVLSGG VGWHIASTVR
PVDSFTQTQV DRGEVDFVHA NGPDRVRLLV QVTNSNATLL SSTSTYVMRI STKPIQITGF
RGLVLVEGEA KLITLQQLNV STNAGAAHVD VKYRVVSPPL YGHIQVYSGN NGDKVSSGVW
SRTDHFFQSH LRDNQLRYLN VDAPDTSGRL IDDRCFAISI EPAVFNISIV KVVVSISTSG
VKLEAGNTGF LLTQHALDVR HYGLVGVSDD DIRFFILTAP VHGNLFYGDT GLRISYGGSF
TLAELRNNRI QYEVDLTRST QPLHDHIELN AVIRDHYRSQ PSTLNITYQP DTKSIQLTSG
LVEVDEGGEV VITSDQLFAQ TLLHNRFAFI ITHQPTHGTL YIINPPNVGN LTTFTTQDIL
EHRLKYRHDG SETPQDFLAF TLHPISGAEE ALISGVLNIS IHLLNDHPPV RVVNQPFHLP
RRGERLLTPH DIWYHDPDIS DDDRELKFVR RGISNGDLLN ATTLMKIFEF SQKDIASSGV
LFRHRGRDFG RFVFWVKDGK HFATGLFVVV ASPPYLRITN HSKLMVERSS SAAVTSNHIS
ISTNVDGWPR NVGFSITSPP AHGNLVIGDS PVTTFTQADI NHGNLIYRHD GSEGKRDIFH
FDIRVGSTTA HGNVSVRIYL ASEMLPPVLK RNEMIVVHQN SSVVLTRSTL RAHHPTTRTK
DLAFTLTRPP VYGSVVVTTS PPSPNITTFT QWDINQGLVV YQQDGNISDD IVAPSDGFEF
TVSNGMMSSM GEVHVEIIPS GIPLRCGNFS VREGGSRILI SDYLGMHNEH YDADNINVRV
VEQPMHGQLE SARDTGVQLR EFPLRLALAE FVYYVHDGSD TLYDSYKLQA STIDGSKTSR
IMTSHITIIP YNDEAPYIVN NTGMEVWVNS TTTINEAQLT AMDPDTPPNV QYSILPPLNG
HLVLSTNPHQ QLHNFTQQQI NDGQLLFVHQ GSYTGGFTFQ VGDGRNYGVK QIFIIRARPL
VISISGSHTM PVFPGTTSAL QPSVMHGSTN SGEGNSHGVT FHVSKPPRKG ELVKLLPPRN
AATVTSFTQE DIEMGAIIYN QTEVLDGWSA FDDIVLSAHS PPAMSVHHIH LSINITYDAY
QHANRMAVVD EGGKVNLTTH HIDASNLLKK YPHAHLHQLR YKVKSIPSCG LVSIQGVMGA
INTTFSQADL VHGRVVYTHD GSEHFKDWFD YVAWVEGASP SAVGDRFTLT ITPVNDNMPV
LITKSPSIEV VQGFVATIGQ NDLEYTDVDN PPQEVRYKVI RPPTHGRIML LTHTTPHPVD
SFTQRDINQR KLIFDQNGSG L
//
