ID H2ZD12_CIOSA Unreviewed; 919 AA.
AC H2ZD12;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=MYND-type domain-containing protein {ECO:0000259|PROSITE:PS50865};
OS Ciona savignyi (Pacific transparent sea squirt).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000015478.1, ECO:0000313|Proteomes:UP000007875};
RN [1] {ECO:0000313|Proteomes:UP000007875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., Ait-zahra M.,
RA Allen N., Allen T., An P., Anderson M., Anderson S., Arachchi H.,
RA Armbruster J., Bachantsang P., Baldwin J., Barry A., Bayul T.,
RA Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., Borowsky M.,
RA Boukhgalter B., Brunache A., Butler J., Calixte N., Calvo S., Camarata J.,
RA Campo K., Chang J., Cheshatsang Y., Citroen M., Collymore A., Considine T.,
RA Cook A., Cooke P., Corum B., Cuomo C., David R., Dawoe T., Degray S.,
RA Dodge S., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A.,
RA Elkins T., Engels R., Erickson J., Farina A., Faro S., Ferreira P.,
RA Fischer H., Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G.,
RA Gnerre S., Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K.,
RA Hafez N., Hagopian D., Hagos B., Hall J., Hatcher B., Heller A.,
RA Higgins H., Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E.,
RA Iliev I., Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M.,
RA Karlsson E., Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E.,
RA Labutti K., Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., Lui A.,
RA Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., Manning J.,
RA Marabella R., Maru K., Matthews C., Mauceli E., Mccarthy M., Mcdonough S.,
RA Mcghee T., Meldrim J., Meneus L., Mesirov J., Mihalev A., Mihova T.,
RA Mikkelsen T., Mlenga V., Moru K., Mozes J., Mulrain L., Munson G.,
RA Naylor J., Newes C., Nguyen C., Nguyen N., Nguyen T., Nicol R., Nielsen C.,
RA Nizzari M., Norbu C., Norbu N., O'donnell P., Okoawo O., O'leary S.,
RA Omotosho B., O'neill K., Osman S., Parker S., Perrin D., Phunkhang P.,
RA Piqani B., Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V.,
RA Raymond C., Retta R., Richardson S., Rise C., Rodriguez J., Rogers J.,
RA Rogov P., Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., Stetson K.,
RA Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., Tenzing P.,
RA Tesfaye S., Theodore J., Thoulutsang Y., Topham K., Towey S., Tsamla T.,
RA Tsomo N., Vallee D., Vassiliev H., Venkataraman V., Vinson J., Vo A.,
RA Wade C., Wang S., Wangchuk T., Wangdi T., Whittaker C., Wilkinson J.,
RA Wu Y., Wyman D., Yadav S., Yang S., Yang X., Yeager S., Yee E., Young G.,
RA Zainoun J., Zembeck L., Zimmer A., Zody M., Lander E.;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAVP00000015478.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2ZD12; -.
DR STRING; 51511.ENSCSAVP00000015478; -.
DR Ensembl; ENSCSAVT00000015656.1; ENSCSAVP00000015478.1; ENSCSAVG00000009083.1.
DR eggNOG; ENOG502QQJP; Eukaryota.
DR GeneTree; ENSGT00460000041630; -.
DR InParanoid; H2ZD12; -.
DR OMA; IYIRWLQ; -.
DR TreeFam; TF328860; -.
DR Proteomes; UP000007875; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR15897; ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1; 1.
DR PANTHER; PTHR15897:SF2; ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF02493; MORN; 4.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00248; ANK; 7.
DR SMART; SM00698; MORN; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT REPEAT 301..333
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 696..728
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 879..919
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 368..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 919 AA; 102442 MW; 84A9BE6341B91E95 CRC64;
KYSGEFVDDM RHGTGSHTWK SGEVYEGSFY KDHMHGNGCY TWRDGSTFTG SFYLDQKQGY
GTLTFVNGDV FEGLYKANER FGPGVLTYAG HGQCKVQDIG WWCRDKLIRL CTRVEGAFSM
HDHKEYKYFE EETHHQIDLS ENESSDLFAH NATSYSFLSE QFKAALSSES TVLPNGIEIY
SKDYEHLPQT SKLKKELNQA FFGADYDLVC SDKLYTVVAI NNTPLSMKIQ KHIHTHRHQE
KGLSFIPDEI STKERSFFDS KSGPLEHASR QLLLCAGAGD AHSVYSILKS GAADPNVADR
QGNNPIISAA TNCHLDVVNI LLDMGANINQ VNDQGTSSLS ACHVFYYPVD HFKTNLLDQI
HAKHPEYGVF EKPKTKKRES IKRRSSSISS KVKNRRESSP SPAPSDDSVS LLDGIGATEG
IEICKSDLKS RSAEKKPKKT KSSKVTEENS VTQDGSSSSD VLHQIFLTEE LAFESNENVV
DLDAKVTQDL IERTATLLSY NERAVSGVST RNGQAIRLGT TGALAVWKAE HSQLRKTIEL
LLLRGADPNI GPVPFPPLFF AVKAADISAV CLLLNKGAST AFRLSDKGLG GFNVLHVASG
IMCSEGVKLV ELLLHANADP NTCAHDRYGI YNKMHTCEGT MTLDDMHKNM DSMGLSEDLG
ITALHIACHR DDNYKDACDV THLLLNNAAK PDCIWTGHSP LSLAIASGND LCVKKLLQFG
ADASLELSDG LGSALCVASD PQYEFRRSPE DRISLIDWLV KFGADMLAPI KFGSKQSTGT
VVDYAHWLFN KDTRISRTPY HALNIKEREA YNARKNLLTH LGKLLRESAK NLDRRTTQEN
FSGSTENGLY PHETDRDDHS VKYAFELCKF FRKPAFKYCY ECGRSVGVHL TSCTRCHEVY
YCSRACKLKA WEERHKYEC
//
