ID H2ZS85_LATCH Unreviewed; 750 AA.
AC H2ZS85;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Cyclin T2 {ECO:0000313|Ensembl:ENSLACP00000000256.1};
GN Name=CCNT2 {ECO:0000313|Ensembl:ENSLACP00000000256.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000000256.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000000256.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
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DR EMBL; AFYH01231428; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01231429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01231430; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01231431; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006011561.1; XM_006011499.2.
DR AlphaFoldDB; H2ZS85; -.
DR STRING; 7897.ENSLACP00000000256; -.
DR Ensembl; ENSLACT00000000258.1; ENSLACP00000000256.1; ENSLACG00000000230.2.
DR GeneID; 102354567; -.
DR KEGG; lcm:102354567; -.
DR CTD; 327568; -.
DR eggNOG; KOG0834; Eukaryota.
DR GeneTree; ENSGT00940000155759; -.
DR HOGENOM; CLU_012994_1_1_1; -.
DR InParanoid; H2ZS85; -.
DR OMA; SCSVKQY; -.
DR OrthoDB; 4848076at2759; -.
DR TreeFam; TF101014; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000000230; Expressed in chordate pharynx and 6 other cell types or tissues.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20596; CYCLIN_CCNT2_rpt1; 1.
DR CDD; cd20598; CYCLIN_CCNT2_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR047321; CYCLIN_CCNT2_rpt1.
DR InterPro; IPR047322; CYCLIN_CCNT2_rpt2.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF43; CYCLIN-T2; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR Pfam; PF21797; CycT2-like_C; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cyclin {ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 42..141
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 259..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 83655 MW; 0C38E7A1DCCBF470 CRC64;
MAACRGSTSR WFYTREQLEN TPSRRCGVEA DKELSYRQQA ANLIQEMGQR LNVSQLTINT
AIVYMHRFYM QHSFTKFHRN TVSPTALFLA AKVEEQPRKL EHVIKVTHAC LNPQEPQLDT
KSDAYLQQAQ ELVILETIML QTLGFEITIE HPHTDVVKCT QLVRASKDLA QTSYFMATNS
LHLTTFCLQY KPTVIACVCI HLACKWSNWE IPVSTDGKHW WEYVDQGVNL ELLDELTHEF
LQILEKTPSR LKKIRNWRAN QAAKKPKTEG QVADNALPGP SMVQNPALVE TVTGMSTNAS
FPKPSTSASF PVPVPLNTGC IPVQTSHGPE STAITAVDIP STSFSSTSQQ EWPQHQEQTR
IESAYSHKQE LHLSAGQQNM TNFQQGPSGQ LLPALHHRGD KSSEHSSSKH EYAHKSSSSK
HHTPVAVPSV PAPQKMTLDK YREKHAAELE IQKRKLETLE MDVKEKYAFA AQALVEQQHK
KHMQPQPQAS GSSSLTSPIK MKIPLANPDR LDKHSSDKKD KGAALKLRIP IPHTEKTSSK
EELKMKIKVS SSDRHSSSDE GSGKSKHSSP HISKEHKEKH KDHSSNRHHS TSSSHKHSHL
YTNSSSSKHS TDGTVPTVLR SPVSLSNEGN SSSSSSSRKR LHSSDVSHNH HSKMSKSSKS
SGSSSSSSSS VKQYVPSHNS VLNLPFPPPP PVTYQVGYGH LSTLVKLDKK PVETTRPDAN
HEFNANSQHM DYKDTFDMLD SLLSAQGMNM
//
