ID   H2ZXK2_LATCH            Unreviewed;       303 AA.
AC   H2ZXK2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE            EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN   Name=SULT5A1 {ECO:0000313|Ensembl:ENSLACP00000002123.1};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000002123.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000002123.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC       {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR   EMBL; AFYH01193548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01193549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H2ZXK2; -.
DR   STRING; 7897.ENSLACP00000002123; -.
DR   Ensembl; ENSLACT00000002139.1; ENSLACP00000002123.1; ENSLACG00000001899.1.
DR   eggNOG; KOG1584; Eukaryota.
DR   GeneTree; ENSGT00940000163403; -.
DR   HOGENOM; CLU_027239_1_0_1; -.
DR   InParanoid; H2ZXK2; -.
DR   OMA; FKSKMQD; -.
DR   TreeFam; TF321745; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR11783:SF212; SULFOTRANSFERASE; 1.
DR   PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT   DOMAIN          53..297
FT                   /note="Sulfotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00685"
SQ   SEQUENCE   303 AA;  35122 MW;  C17F3604BEFA81F1 CRC64;
     ESSNSSSSIT TAAADQESMD RMEVVETLCG INLPGHLHTK ESLQFAQDFE FRDNDVVIVT
     YPKSGTTWMQ EILTLIYSKG DSMPAENIPN WARAPWLEQH YFKDLVRNGS GPRLITTHLQ
     YRFLAKALGR SKAKVIYITR NPKDVAVSFY HFHKMANFLP DPGSFNDLLK KFLDGTVSFG
     SWFDHVKGWH NQKNAVNIFY ITYEEMKMDL RGSIERLCNF LHFPLLPAVV DSIHKHCTFT
     NMKDNKMANY TLIPNEIMDH QKGKFMRKGE VGDWKRHFTV EQSIIFDNIY EDEMRGTSLQ
     FTW
//