ID H3A1N6_LATCH Unreviewed; 186 AA.
AC H3A1N6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=ADP ribosylation factor like GTPase 8B {ECO:0008006|Google:ProtNLM};
GN Name=LOC102354041 {ECO:0000313|Ensembl:ENSLACP00000003557.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000003557.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000003557.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004608}. Late endosome membrane
CC {ECO:0000256|ARBA:ARBA00004414}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004656}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290, ECO:0000256|RuleBase:RU003925}.
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DR EMBL; AFYH01252775; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01252776; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01252777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01252778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01252779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006013177.1; XM_006013115.2.
DR AlphaFoldDB; H3A1N6; -.
DR STRING; 7897.ENSLACP00000003557; -.
DR Ensembl; ENSLACT00000003589.1; ENSLACP00000003557.1; ENSLACG00000003169.1.
DR GeneID; 102354041; -.
DR KEGG; lcm:102354041; -.
DR eggNOG; KOG0075; Eukaryota.
DR GeneTree; ENSGT00940000165940; -.
DR HOGENOM; CLU_040729_10_0_1; -.
DR InParanoid; H3A1N6; -.
DR OMA; FRNMWER; -.
DR OrthoDB; 607297at2759; -.
DR TreeFam; TF105470; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000003169; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR CDD; cd04159; Arl10_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR044154; Arl8a/8b.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45732:SF20; ADP-RIBOSYLATION FACTOR-LIKE 10B ISOFORM X1; 1.
DR PANTHER; PTHR45732; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51419; RAB; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022618};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003925};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003925};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
SQ SEQUENCE 186 AA; 21425 MW; 41239F625CEFC99C CRC64;
MLALINKLLD WFKSLFWKEE MELTLVGLQY SGKTTFVNVI ASGQFNEDMI PTVGFNMKKI
TKGNVTIKVW DIGGQPRFRS MWERYCRGVN AIVYMVDAAD MDKVEASKNE LHNLLEKPQL
QGIPVLVLGN KRDLQNALDE KELIEKLNLS AIQDREICCY SVSCKEKDNI DITLQWLIQH
SKSRHC
//
