ID H3A775_LATCH Unreviewed; 519 AA.
AC H3A775;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=HTH CENPB-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=LOC102359281 {ECO:0000313|Ensembl:ENSLACP00000005496.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000005496.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000005496.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
CC -!- SIMILARITY: Belongs to the tigger transposable element derived protein
CC family. {ECO:0000256|ARBA:ARBA00010881}.
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DR EMBL; AFYH01224137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A775; -.
DR Ensembl; ENSLACT00000005544.1; ENSLACP00000005496.1; ENSLACG00000004887.1.
DR eggNOG; KOG3105; Eukaryota.
DR GeneTree; ENSGT00940000154420; -.
DR HOGENOM; CLU_018294_1_1_1; -.
DR InParanoid; H3A775; -.
DR OMA; SACCIER; -.
DR TreeFam; TF101131; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000004887; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR19303:SF56; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 1..49
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 63..135
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 25..45
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
SQ SEQUENCE 519 AA; 59203 MW; 6719B792118D5138 CRC64;
KRKRKAFTIK DKMFAIDLIK NGESQANVAR YLNVAESTVR GWLKNEGKLI SFLHEVNTSD
GLTRKKARSA KDSDLDFSLY AWFMQERQLG MPISGPILRA QAERFNRQLG GPSNFKASQG
WLHRFQKRHG ISISGRITND RAAVELFQSE LKKVIEEVGY TDEQIYNCDE TGLCFKLLPD
RSMAVNLGLH KGEGFKKLKD RVTVLFCINK KGNHKLKPLC VGKSEKPRCF HHVNMNNLPF
AYTHSKNACM TPAIFEEWFY QEFVPEVRHF LRNRNLEEKA MLLLDHCPAH PPAENLVTRD
GRIRVLFLPK NAASEVQPLD QGIISTFKMN FRCELAQAML NSEKSVAEFL RELNLKEMFY
LGGHAWGVIT SIFIEKTWMK ALGPSFHMEE ESISEPHNVV ECEEEGDLRG FAAAEINDLS
DDDIKKWALA DDSCPTAELL VDEDMENRTS AADGIKTEDS NHAQDVEQVA VYDESDDIEP
PPSAFEAYRS LELGLRWLET QDIEPVKVLQ LRSIVDFAR
//
