ID H3ABX2_LATCH Unreviewed; 829 AA.
AC H3ABX2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
GN Name=COG3 {ECO:0000313|Ensembl:ENSLACP00000007143.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000007143.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000007143.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in ER-Golgi transport.
CC {ECO:0000256|ARBA:ARBA00002090}.
CC -!- SIMILARITY: Belongs to the COG3 family.
CC {ECO:0000256|ARBA:ARBA00009936}.
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DR EMBL; AFYH01204791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01204792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01204793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01204794; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01204795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01204796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ABX2; -.
DR STRING; 7897.ENSLACP00000007143; -.
DR Ensembl; ENSLACT00000007202.1; ENSLACP00000007143.1; ENSLACG00000006338.1.
DR eggNOG; KOG2604; Eukaryota.
DR GeneTree; ENSGT00390000015682; -.
DR HOGENOM; CLU_011639_1_1_1; -.
DR InParanoid; H3ABX2; -.
DR OMA; DEFELWG; -.
DR TreeFam; TF314200; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000006338; Expressed in pectoral fin.
DR GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR InterPro; IPR048685; COG3_C.
DR InterPro; IPR048320; COG3_N.
DR InterPro; IPR007265; COG_su3.
DR PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR Pfam; PF20671; COG3_C; 1.
DR Pfam; PF04136; COG3_N; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 129..272
FT /note="Conserved oligomeric Golgi complex subunit 3 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04136"
FT DOMAIN 293..642
FT /note="Conserved oligomeric Golgi complex subunit 3 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20671"
SQ SEQUENCE 829 AA; 94598 MW; 1D91F80090094A1F CRC64;
RGGMMADQAA LELLEKETRE KLASWDRRSD PLAPLTEAQT DSFLELKAAI ENLPLPAELP
IEDLCSLTSR VTIPITAAIP ESTEDILLKG FAALGMEDDR IETAQQFFSW FSKLQTAMDQ
DEGEAYRQMR DYLYGFQEQC DAILNDVNSA LQHLESLQKQ YLFVSTKTGT LHEACEQLLK
EQSELVDLAE SIRQKLSYFN ELENINTKLN SSTLSVNNEG FIPMLAKLDE CIVYVSSHPN
FKDYPMYLNK FKQCLSKAIH LLKTHTVNTL QNLTNQLIKR DPSVTSNTEN AFTLYYVKFR
AAAPKVRTLI EQVEQRAEKI PEYQQLLNEI HQCYLDQREQ LLGPSITSTI TDLTSQNNRD
HCALVRSGCA FMVHVCQDEH QLYNEFFTRP TPRLDELLER LCLSLYDVLR PLIIHVIHLE
TLSELCGILK NEMLEDHVQN NVVHLGAFAT LVKQMLEDVQ ERLVYRTHIY IQTDIMGYKP
APGDLAYPEK LEMMEQIALS LKEEQKKLPA PEASFSDVQL EDPDSKIVIK SVGASEPLNT
RPQASISPAD LHGMWYPTVR RTLVCLSKLY RCIDRTVFQG LSQEALSACI QSLLGAADSI
TKNKTQVDGQ LFLIKHLLIL REQIAPFHAE FTIKEISLDL RKTRDAAFKM LNPKAVPRFF
RLNSNNALLE FLLEGTPEIK EHYIDSKKDV DRHLKSACEQ FIQQQTKLFV EQLEEFMTKV
KTLKTMASQG GPKYSLSQQP WAQPAKINDV VASTYKTMKT KLPVTLRSMA LYLANKDTEF
ILFKPVRNNI QQVFQKLHAM LQEEFSGEDL QIIACPSMEQ VNLLLSVSK
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