GenomeNet

Database: UniProt
Entry: H3AQR6_LATCH
LinkDB: H3AQR6_LATCH
Original site: H3AQR6_LATCH 
ID   H3AQR6_LATCH            Unreviewed;       636 AA.
AC   H3AQR6;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   25-OCT-2017, entry version 45.
DE   SubName: Full=Potassium voltage-gated channel subfamily D member 1 {ECO:0000313|Ensembl:ENSLACP00000011987};
GN   Name=KCND1 {ECO:0000313|Ensembl:ENSLACP00000011987};
OS   Latimeria chalumnae (West Indian ocean coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000011987, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Ensembl:ENSLACP00000011987}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000011987};
RX   PubMed=9215903;
RA   Zardoya R., Meyer A.;
RT   "The complete DNA sequence of the mitochondrial genome of a 'living
RT   fossil,' the coelacanth (Latimeria chalumnae).";
RL   Genetics 146:995-1010(1997).
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000011987}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSLACP00000011987}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AFYH01161524; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161525; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161526; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161527; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161528; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161529; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161531; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01161533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3AQR6; -.
DR   STRING; 7897.ENSLACP00000011987; -.
DR   Ensembl; ENSLACT00000012078; ENSLACP00000011987; ENSLACG00000010550.
DR   eggNOG; KOG4390; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   InParanoid; H3AQR6; -.
DR   OMA; PLAFFCM; -.
DR   OrthoDB; EOG091G18X0; -.
DR   TreeFam; TF313103; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003975; K_chnl_volt-dep_Kv4.
DR   InterPro; IPR004054; K_chnl_volt-dep_Kv4.1.
DR   InterPro; IPR024587; K_chnl_volt-dep_Kv4_C.
DR   InterPro; IPR021645; Shal-type_N.
DR   InterPro; IPR011333; SKP1/BTB/POZ.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 2.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF11879; DUF3399; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF11601; Shal-type; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01516; KV41CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01497; SHALCHANNEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008672};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00091688}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    636       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003579396.
FT   TRANSMEM    183    204       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    224    245       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    257    279       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    324    345       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    357    373       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    385    406       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       38    107       BTB. {ECO:0000259|PROSITE:PS50097}.
FT   COILED      133    157       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   636 AA;  71968 MW;  6837D4C168BFC1D3 CRC64;
     MAAGVATWLP FARAAAVGWL PLAKKNMPRP PSDKKRRNDE ILVVNVSGRR FQTWKNTLDR
     YPDTLLGSSE KEFFFNEETQ EYFFDRDPEM FRHILNFYRT GKLHYPRHEC ISAFDEELSF
     FGIIPEIIGD CCLEEYRDRK KENAERLAED NEAEMATDAP LPPHSTFRQK LWRAFENPHT
     STMALVFYYV TGFFIAVSVI ANVVETVPCR PFPGRKKDLP CGEKYSLAFF CMDTACVMIF
     TFEYLMRLFA APNRCKFMRS VMSIIDVVAI MPYYIGLVMP ENEDVSGAFV TLRVFRVFRI
     FKFSRHSQGL RILGYTLKSC ASELGFLLFS LTMAIIIFAT VMFYAEKGTK PSTFTSIPAS
     FWYTIVTMTT LGYGDMVPTT IAGKIFGSIC SLSGVLVIAL PVPVIVSNFS RIYHQNQRAD
     KRKAQQKVRL ARIRLAKSGT TNAFMQYKQN GAFEDPDNGS QALCIRNRSS FEQQHHHLLH
     CLEKTTNHEF TDEQTYSEVC MAESMGYRTS RSTSVSSHQG LGTSCCPRRA KKRAIRLANS
     TVSVSRGSMQ ELDTLQIQKT TVPQHCSRSS LNARTHDNMK LNCETSDLTA AIISIPTPPG
     NTPDESQPPS PVMAGILRNS SLTTTYTQET VKISSL
//
DBGET integrated database retrieval system