ID H3ARJ0_LATCH Unreviewed; 645 AA.
AC H3ARJ0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Influenza virus NS1A binding protein {ECO:0000313|Ensembl:ENSLACP00000012261.1};
GN Name=IVNS1ABP {ECO:0000313|Ensembl:ENSLACP00000012261.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012261.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012261.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; AFYH01082543; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01082544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01082545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01082546; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01082547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01082548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ARJ0; -.
DR STRING; 7897.ENSLACP00000012261; -.
DR Ensembl; ENSLACT00000012353.1; ENSLACP00000012261.1; ENSLACG00000010793.1.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000155635; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; H3ARJ0; -.
DR OMA; TEIVQDY; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000010793; Expressed in muscle tissue and 6 other cell types or tissues.
DR CDD; cd18502; BACK_NS1BP_IVNS1ABP; 1.
DR CDD; cd18306; BTB_POZ_NS1BP; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 2.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 32..99
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 256..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 72162 MW; FEC33E6DD1E5F0DC CRC64;
MIPNGCLSFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEM
FNSDSDPHGI SHVKFDDLNP KAVEVLLHYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV
CGDYLLSKMG TESCISYRNF ASHMGDSRLL GNIDAYIQHH LLDVSEEEEF LKLPRLKLEV
ILEENVCLPS NGKLYTKVIN WVQCSIWENG ETLEDLIAEV QTLYYSADHK LLDGNLLDGQ
AEVFGSDDDH IQFVQKKPPR ENPHKQMSSS SSGSLSSPGA TVPSSKHEWK IIASKKTSSN
TYLCLAVLDG VLCVIFLHGR NSPQSSPSST PCLLKSMSFE TQPDPIEKLL SPMHYARSGL
GTAELNGKLI AAGGYNREEC LRTVECYDPW EDCWTFIAPM RTPRARFQMA VLMDKLYVMG
GSNGHSDELS CGESYDPHTD DWTQVPELRT NRCNAVIGVC SLNGKLYIVG GSDPFGQKGL
KNCDAFDPVM KSWTSCAPLN IRKVQLSRIC EFYKYIYFFK KAANILNSPK RSNKKKKKKI
ILIVSDLPDV RNASGPRCLA SDELFAIGGF DGSHALSCVE MYDPSTNEWK MMGNMTSSRT
NAGVAVVQNL IYAVGGFDGN EFLNTMEVYK PETNEWTPYM RIFNF
//
