ID H3AT85_LATCH Unreviewed; 256 AA.
AC H3AT85;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member {ECO:0000256|RuleBase:RU369103};
GN Name=ANP32E {ECO:0000313|Ensembl:ENSLACP00000012856.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012856.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012856.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Multifunctional protein that is involved in the regulation of
CC many processes. {ECO:0000256|RuleBase:RU369103}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|RuleBase:RU369103}.
CC -!- SIMILARITY: Belongs to the ANP32 family.
CC {ECO:0000256|ARBA:ARBA00025777, ECO:0000256|RuleBase:RU369103}.
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DR EMBL; AFYH01122226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01122227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01122228; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01122229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01122230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01122231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006001631.1; XM_006001569.2.
DR AlphaFoldDB; H3AT85; -.
DR STRING; 7897.ENSLACP00000012856; -.
DR Ensembl; ENSLACT00000012950.1; ENSLACP00000012856.1; ENSLACG00000011320.1.
DR GeneID; 102346644; -.
DR KEGG; lcm:102346644; -.
DR CTD; 81611; -.
DR eggNOG; KOG2739; Eukaryota.
DR GeneTree; ENSGT00950000182907; -.
DR HOGENOM; CLU_063314_1_1_1; -.
DR InParanoid; H3AT85; -.
DR OMA; MPNNQVS; -.
DR OrthoDB; 1386993at2759; -.
DR TreeFam; TF317206; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000011320; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR045081; AN32.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR PANTHER; PTHR11375; ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32; 1.
DR PANTHER; PTHR11375:SF5; ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00446; LRRcap; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614,
KW ECO:0000256|RuleBase:RU369103}; Nucleus {ECO:0000256|RuleBase:RU369103};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 128..146
FT /note="U2A'/phosphoprotein 32 family A C-terminal"
FT /evidence="ECO:0000259|SMART:SM00446"
FT REGION 148..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..197
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..233
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 256 AA; 28940 MW; 43C4D5E3D872A918 CRC64;
MEMKKKVSLD MRSRTPSEVR ELVIDNCQSA DGEIEGVTEN FKELEFLSMV NVGLTSLSKL
PSLAKLRKLE LGDNSISGGL EILSEKCPNL TYINLSGNKI KDLSSIEPLQ NLKSLKSLDL
FNCAITNLKE YRESIFQLLP QLTYLDGFDQ EDNEAPDSEA EGEEDEEDEE DEAGPPGEYE
EDDEEEEGSE VGEEEEEGVG LSYLMKEEIH DEEDDDDYVE GEEDEEDEED DEEEGVRGQK
RKRDLEDDGD GEEDED
//
