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Database: UniProt
Entry: H3AU39_LATCH
LinkDB: H3AU39_LATCH
Original site: H3AU39_LATCH 
ID   H3AU39_LATCH            Unreviewed;       401 AA.
AC   H3AU39;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   30-AUG-2017, entry version 21.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Latimeria chalumnae (West Indian ocean coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013160, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Ensembl:ENSLACP00000013160}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000013160};
RX   PubMed=9215903;
RA   Zardoya R., Meyer A.;
RT   "The complete DNA sequence of the mitochondrial genome of a 'living
RT   fossil,' the coelacanth (Latimeria chalumnae).";
RL   Genetics 146:995-1010(1997).
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000013160}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSLACP00000013160}.
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DR   EMBL; AFYH01100453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01100454; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01100455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01100456; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01100457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7897.ENSLACP00000013160; -.
DR   Ensembl; ENSLACT00000013256; ENSLACP00000013160; ENSLACG00000011590.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   GeneTree; ENSGT00390000004941; -.
DR   InParanoid; H3AU39; -.
DR   OMA; CPVSDLP; -.
DR   OrthoDB; EOG093702RP; -.
DR   TreeFam; TF300346; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008672};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   COILED       94    121       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   401 AA;  45116 MW;  3D09DC636BBDA3EA CRC64;
     MGSLFRSEEI CLAQLFLHSG SAYNCVSELG EIGVVEFRDL NQNVNAFQRR FVGEVRRCED
     MEKTFSFLEQ EVRKVGLSVQ EGETNPPAPL SRDVLKIQEE SEQLAQELRE VSRNRDSLHA
     RLLELRQYAQ VLKETQNMLG HSGPMPMGSP PRRRHHSDID PLINPSTSQG QEAKLSTHTH
     THTHTHTHTH TQLCWERGRG VITFVFVVSP PPLSLSFLQG EMVTWVVFVV SYWGEQIAQK
     VKKICDCCGF AMAIGPADEM GVSNRVTYTR LKPSLAARML VLGQTEDYLK QILAKVLMSL
     HSWSVQVKKM KAIYMILNQC SFNVTEKCLI AEVWCPVSDL PKLQHALAEG SRKSGTGVNS
     FVNRIPSTDN PPTLNRTNKF TSGFQNIVDA YGIASYQEVN P
//
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