ID   H3AUI0_LATCH            Unreviewed;       572 AA.
AC   H3AUI0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013301.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000013301.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AFYH01172420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01172421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7897.ENSLACP00000013301; -.
DR   Ensembl; ENSLACT00000013397.1; ENSLACP00000013301.1; ENSLACG00000011711.1.
DR   eggNOG; ENOG502SBIG; Eukaryota.
DR   GeneTree; ENSGT01100000263573; -.
DR   HOGENOM; CLU_002274_3_2_1; -.
DR   InParanoid; H3AUI0; -.
DR   OMA; SENMHEV; -.
DR   TreeFam; TF352120; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   Bgee; ENSLACG00000011711; Expressed in pharyngeal gill and 1 other cell type or tissue.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR   PANTHER; PTHR45690:SF15; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          107..244
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   572 AA;  66724 MW;  B3F5311713D556AD CRC64;
     ANTTLRDHII EFQNLYKESL LKEAELIKTY PLPGRRKQEE VSLMDLYTEL MVVDTQFEST
     WSENMHEVLN RGELHAKLLK EKVHKTHERI RDYQLFRRSY ETIEFPLTIV ISGVPGIGKT
     TLVQKILYDW AAGEHHQRFS FIFLFKFRDL NHWREPTSLA ELIVKHHPCL NDDSLQKVLR
     KPENLLFIFD GLDESRTSIN FKDKLLQTYR NPEHLTTIST IVTSLIGQTV LKGCSVVITS
     RPTALESSNI KSVQRCTEII GFLAEQRKIY FKRFFSDEKV SMEAFEYVQQ NDILYTMCFN
     PSYCWILCSV LKSYFTKENK HQQRPKTISQ LXEADNPRDL LTSISKLALY GVRNKCLVFD
     DRDMDSFRIQ SSQFLTGFMK EILQKEESFN RLVYTYLHLT VQEFLAALSP LLDTTADMTE
     LLNKADSYED GRCEILLRFL SGLCHTGTRD KFTETLGPLS IESICKVIDW LKTKTERELQ
     QDLLSEKRYN RELLNILHCL YETQNTTLIR STVGNQKSLQ LNKLNLNPVD CYVLSNILNC
     CREIESLDFS ESRLGEEEFS KLKPGLNKCK II
//