ID H3AUK5_LATCH Unreviewed; 207 AA.
AC H3AUK5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU369086};
GN Name=POLR3H {ECO:0000313|Ensembl:ENSLACP00000013326.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013326.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000013326.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: DNA-dependent RNA polymerase which catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. {ECO:0000256|RuleBase:RU369086}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369086}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit
CC family. {ECO:0000256|ARBA:ARBA00009307}.
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DR EMBL; AFYH01125376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01125377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01125378; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AUK5; -.
DR STRING; 7897.ENSLACP00000013326; -.
DR Ensembl; ENSLACT00000013422.1; ENSLACP00000013326.1; ENSLACG00000011734.1.
DR eggNOG; KOG3297; Eukaryota.
DR GeneTree; ENSGT00390000004383; -.
DR HOGENOM; CLU_073901_1_0_1; -.
DR InParanoid; H3AUK5; -.
DR OMA; LGPTLWW; -.
DR TreeFam; TF103053; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000011734; Expressed in chordate pharynx and 1 other cell type or tissue.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule.
DR CDD; cd04330; RNAP_III_Rpc25_N; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.30.1490.120; RNA polymerase Rpb7-like, N-terminal domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR013238; RNA_pol_III_Rbc25.
DR InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf.
DR InterPro; IPR004519; RNAP_E/RPC8.
DR InterPro; IPR045113; Rpb7-like.
DR InterPro; IPR005576; Rpb7-like_N.
DR NCBIfam; TIGR00448; rpoE; 1.
DR PANTHER; PTHR12709; DNA-DIRECTED RNA POLYMERASE II, III; 1.
DR PANTHER; PTHR12709:SF1; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8; 1.
DR Pfam; PF08292; RNA_pol_Rbc25; 1.
DR Pfam; PF03876; SHS2_Rpb7-N; 1.
DR SUPFAM; SSF88798; N-terminal, heterodimerisation domain of RBP7 (RpoE); 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU369086}; Nucleus {ECO:0000256|RuleBase:RU369086};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU369086}.
FT DOMAIN 9..68
FT /note="RNA polymerase Rpb7-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03876"
FT DOMAIN 87..204
FT /note="RNA polymerase III subunit Rpc25"
FT /evidence="ECO:0000259|Pfam:PF08292"
FT REGION 164..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 207 AA; 23543 MW; CEAF78F20DC7BC84 CRC64;
MFVLVEMVDT VRIPPWQFER KLNDAIAEEL NKKLANKFPR QVVYNIGLCI CLYDITKLED
SYIFPGDGAS HTKVHFRYVV FRPFLDEILI GKIKGCSADG VQVSLGFFDD ILIPPESLQQ
PAKFDEAEQV WVWEYETEEG AHDLYMDSEE DIRFRVVFDS FIDTSPTGPS SDEASTSEEG
QKKEAPYTLI GSISEPGLGL LSWWTNS
//
