ID H3AV88_LATCH Unreviewed; 872 AA.
AC H3AV88;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=NOP14 nucleolar protein {ECO:0000313|Ensembl:ENSLACP00000013559.1};
GN Name=NOP14 {ECO:0000313|Ensembl:ENSLACP00000013559.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013559.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000013559.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Has a role in the nuclear export of 40S pre-ribosomal subunit to the
CC cytoplasm. {ECO:0000256|ARBA:ARBA00024695}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP14 family.
CC {ECO:0000256|ARBA:ARBA00007466}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFYH01091016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091017; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091018; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091021; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AV88; -.
DR STRING; 7897.ENSLACP00000013559; -.
DR Ensembl; ENSLACT00000013655.1; ENSLACP00000013559.1; ENSLACG00000011939.1.
DR eggNOG; KOG2147; Eukaryota.
DR GeneTree; ENSGT00390000017459; -.
DR HOGENOM; CLU_008874_1_1_1; -.
DR InParanoid; H3AV88; -.
DR OMA; FTFPCPQ; -.
DR TreeFam; TF105698; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000011939; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR007276; Nop14.
DR PANTHER; PTHR23183; NOP14; 1.
DR PANTHER; PTHR23183:SF0; NUCLEOLAR PROTEIN 14; 1.
DR Pfam; PF04147; Nop14; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 191..218
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..398
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 872 AA; 100083 MW; 1C03C820F32C2BE4 CRC64;
MGKPQKKNLS EKIRKAKTST SIKNNPFEVK INKQKFNILG RKTKHDHGLP GVSRSKAIKK
RKETLLNEYK QKDKSNTFID KRFGEYDTKL APEEKMMKRF ALERQRNHEK KNIYNLNEDE
ELTHYGQSLA DIEKLKDIPD SDSDTEEKGM LSAELTAAHF GGGGGLLKKK APSEQTEKEE
EQKPKSRKEL IEELIAKSKQ EKRERQTQRE EALELTEKLD KEWKEIQALM PHKTPKSARE
KPEEEKPKPD EYDMIVRQLG FEMKAQPSDR MKTEEELARE EQERLEKLEA ERLRRMRGDL
EDETSSRPKH MSADDLNDGF ILDKEDKRFL AYKDSKLTEE AGEEDKSEEE ESGNEAEEGV
SERGNEEGSE EEAEVDTEEE ESEGEDSHSD LESEIGSEED EHANEKTEKK KSKGLCEEGK
KAVIEAAADE IPFTFAAPGS YDDLKSLLTG HSAENQCTII QRIQKCNHPS LAVGNKAKLE
KLFGFLLEYV GELATKQPPE MRIIDKMVPH LYSLCQMFPE TAAKCVQTVL RDSAHEMEEL
LEVKGRVAFP GLEMIMLMKL KGLFLHFSSF PPVLAPTLSL THTHTHTHTH THTPCPVTSL
QDVATGLFVC CLFLQYVSLS QRFVPELINF LLGILHLAVP NKGTPEYILV PPFKSVGKTS
ELLVVKDKTV MESWKKQHLP LSALQVLEGK DELQLNHFRL SCIATCLDLV KKCITLYGQL
TAFQEIIQPI RILLTKQPFT EEYPPEIQVL HEEVLREIEN KPKQYSPLVF ERKKPVPLKL
YTPKIVEILD FGKNKGGSRQ EREQKRLIHK HKREFKGAVR EIRKDSQFLA RQQLSETLER
DAERKRKVKE LFGSLATQEG EWKALKKKKL KG
//
