ID H3AWB0_LATCH Unreviewed; 206 AA.
AC H3AWB0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Ras-related protein Rab-8B {ECO:0000256|ARBA:ARBA00039498};
GN Name=RAB8B {ECO:0000313|Ensembl:ENSLACP00000013931.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000013931.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000013931.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, phagosome membrane
CC {ECO:0000256|ARBA:ARBA00004616}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004616}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004616}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR EMBL; AFYH01009547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01009548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01009549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01009550; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AWB0; -.
DR Ensembl; ENSLACT00000014030.1; ENSLACP00000013931.1; ENSLACG00000012265.1.
DR GeneTree; ENSGT00940000155363; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000012265; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47980; LD44762P; 1.
DR PANTHER; PTHR47980:SF6; RAS-RELATED PROTEIN RAB-8B; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
SQ SEQUENCE 206 AA; 23854 MW; A86CB8B2A4F0032C CRC64;
VLKPYNYSYF FFFLVEVGEN RSFIMWKKMQ LSLSLSFFVF TGIDFKIRTV ELDGKKIKLQ
IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIK NWIRNIEEHA SSDVERMILG
NKCDMNEKRQ VSKERGEKLA IDYGIKFLET SAKSSINVEQ AFFTLAGDIM TKLNRKMNDS
NSPGGGGPVK IESRSKKSSF FRCMLL
//
