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Database: UniProt
Entry: H3AZ90_LATCH
LinkDB: H3AZ90_LATCH
Original site: H3AZ90_LATCH 
ID   H3AZ90_LATCH            Unreviewed;       586 AA.
AC   H3AZ90;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   25-OCT-2017, entry version 38.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000014961};
OS   Latimeria chalumnae (West Indian ocean coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000014961, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Ensembl:ENSLACP00000014961}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000014961};
RX   PubMed=9215903;
RA   Zardoya R., Meyer A.;
RT   "The complete DNA sequence of the mitochondrial genome of a 'living
RT   fossil,' the coelacanth (Latimeria chalumnae).";
RL   Genetics 146:995-1010(1997).
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000014961}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSLACP00000014961}.
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DR   EMBL; AFYH01131307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01131308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01131309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01131310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01131311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; H3AZ90; -.
DR   STRING; 7897.ENSLACP00000014961; -.
DR   Ensembl; ENSLACT00000015066; ENSLACP00000014961; ENSLACG00000013168.
DR   eggNOG; KOG3676; Eukaryota.
DR   eggNOG; ENOG4110DG4; LUCA.
DR   GeneTree; ENSGT00550000074425; -.
DR   InParanoid; H3AZ90; -.
DR   OMA; QFSIMIQ; -.
DR   OrthoDB; EOG091G0314; -.
DR   TreeFam; TF314711; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR024862; TRPV.
DR   InterPro; IPR008344; TRPV5/TRPV6.
DR   PANTHER; PTHR10582; PTHR10582; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01765; ECACCHANNEL.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008672};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    280    301       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    333    354       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    375    395       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    401    419       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    440    462       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    504    525       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    214       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT       68     95       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      115    147       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
SQ   SEQUENCE   586 AA;  66916 MW;  62F5DE8611465D6F CRC64;
     LFRAARTNDV ATMVLLLEQK DINPFTRGNL EETILHTALL NDKKEVAEVI LDMVPSLINE
     PMTSDMYRGE TPLHIAILRQ DLESVKELLK RGADVVHAQA SGTCFVPGAE CQCYFGEFVL
     SFAACLGNES IVKILIRHNA PLKAQDNLGN TVLHVLVLQK DKEMAYRMYD LITSLVSQEQ
     RQLVENIENN EGLTPLKLAA SQGDPAMFNY LVQRQKKTYW TMGTISYCVY DLTNIDTWGD
     HKSVLDIITS SKKSDVHKLV DAKPVKELLN QKWRSFGYKY FIIWMCSYIL YIVIFTAVSL
     YRPLKPVPKE KSDNVTIMQQ KTLVESYLTT NDYVRLVGEL ITIIGAMVIL ISEVPYLFRI
     GIRNYIGNTS IGGPFPLLMV GYSLLVFIAV VLRILGNGKE SIPLSVALII GWCNTIYFAR
     GFKMLGQFSI MIQKIIFGDL LQWCCLLFIS IIGFTSAFYV MFQTLDLNNY LHFKDFPRTM
     YTIVELTMGL VDLPVPIDKP TPPIIYIVYS VYMIFAYLLM LNLLIAMMDD TYWRIAQERE
     ELWKVQIAAT ILLLERRVPR FLRKRSGVPG SVLGFDDDKW YMGVEE
//
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