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Database: UniProt
Entry: H3B2G0_LATCH
LinkDB: H3B2G0_LATCH
Original site: H3B2G0_LATCH 
ID   H3B2G0_LATCH            Unreviewed;       967 AA.
AC   H3B2G0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   20-DEC-2017, entry version 33.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000016081};
OS   Latimeria chalumnae (West Indian ocean coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000016081, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Ensembl:ENSLACP00000016081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000016081};
RX   PubMed=9215903;
RA   Zardoya R., Meyer A.;
RT   "The complete DNA sequence of the mitochondrial genome of a 'living
RT   fossil,' the coelacanth (Latimeria chalumnae).";
RL   Genetics 146:995-1010(1997).
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000016081}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSLACP00000016081}.
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DR   EMBL; AFYH01020880; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020881; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020882; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020883; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020884; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020885; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020886; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020887; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01020889; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7897.ENSLACP00000016081; -.
DR   Ensembl; ENSLACT00000016192; ENSLACP00000016081; ENSLACG00000014164.
DR   eggNOG; ENOG410IT0D; Eukaryota.
DR   eggNOG; ENOG410YBM8; LUCA.
DR   GeneTree; ENSGT00760000119152; -.
DR   InParanoid; H3B2G0; -.
DR   OMA; CYMYLAC; -.
DR   OrthoDB; EOG091G00T0; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008672};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    967       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003580420.
FT   DOMAIN       49    104       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      111    156       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      164    219       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      225    284       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      290    347       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      539    749       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      411    431       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   967 AA;  108513 MW;  39C5F9A4D88CA1C1 CRC64;
     MISLCLFLLE SSVAFCIDSP PNLRKTLTQK KKKSLEIKFK LKTAQGGGHR TLLYGHAVLL
     RHSYSGMYLC CLSTSRSSTD KLAFDVGLQE DTTGEACWWT IHPASKQRSE GEKVRVGDDL
     ILVSVSSERY LHLSYGNGSL HVDAAFQQTL WSVAPISSGS EVAQGYLIGG DVLRLLHGHM
     DECLTVPSGE HGEEQRRTVH YEGGAVSIHA RSLWRLETLR VAWSGSHIRW GQPFRLRHVT
     TGKYLSLMDD KGLLLMDKEK ADVKSTAFCF RSSKEKLDFG IRKEVDGMGV PEIKYGDSLS
     YIQHVDTGLW LTYQSVDAKS VRMGSVQRKA IMHHEGHMDD GLTLSRSQHE ESRTARVIRS
     TVFLFNKFIR GLDALSKKGK SSNIYLPIES VSLSLQDLIG YFQPPDEHLE HEDKQNRLRA
     LKNRQNLFQE EGMINLALEC INRLHIYSSA AHFADVAGKE AGEAWKSILN SLYELLVAAL
     IRGNRKNCAQ FSGSLDWLIS RLERLEASSG ILEVLHCVLV ESPEALNIIK EGHIKSIISL
     LDKHGRNHKV LDVLCSLCVC HGVAVRSNQH LICDNLLPGR DLLLQTRLVN HVSSMQPNIF
     LGISEGSAQY RKWYYELIVD QVEPFVTAEA THLRVGWAST DGYSPYPGGG EGWGGNGVGD
     DLYSYGFDGL HLWSGCIART VNSPNQHLLK AEDVISCCLD LSAPSISFRI NGQPVQGMFE
     NFNTDGLFFP VVSFSAGVKV RFLLGGRHGE FKFLPPHGYA PCFEALLPKE KMRVEHNKEY
     KQDHSGMRDL LGPTISLTQA AFTPTPVDTS QIVLPPHLER IREKLAENIH ELWVMNKIEL
     GWTFGPVRDD NKRQHPCLVE FSKLPEQERN YNLQMSLETL KTLLALGCHV GIADEHAEDK
     VKKLKLPTKY QLPSEYKPAP MDLSHLKLTS AQEAMVDKLA ENAHNVWARD RIRQGWTYGI
     QQVGTFF
//
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