ID H3B3Y4_LATCH Unreviewed; 779 AA.
AC H3B3Y4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000016605.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000016605.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01099554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B3Y4; -.
DR STRING; 7897.ENSLACP00000016605; -.
DR Ensembl; ENSLACT00000016719.1; ENSLACP00000016605.1; ENSLACG00000014632.1.
DR eggNOG; KOG3627; Eukaryota.
DR GeneTree; ENSGT01050000244883; -.
DR HOGENOM; CLU_359679_0_0_1; -.
DR InParanoid; H3B3Y4; -.
DR OMA; PTMICAY; -.
DR TreeFam; TF331065; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 3.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 5.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24264:SF15; RIKEN CDNA 2210010C04 GENE; 1.
DR PANTHER; PTHR24264; TRYPSIN-RELATED; 1.
DR Pfam; PF00089; Trypsin; 3.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 3.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 3.
DR PROSITE; PS50240; TRYPSIN_DOM; 3.
DR PROSITE; PS00134; TRYPSIN_HIS; 2.
DR PROSITE; PS00135; TRYPSIN_SER; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU363034}.
FT DOMAIN 2..227
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT DOMAIN 293..517
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT DOMAIN 527..778
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 779 AA; 85343 MW; C8E794ED39EAFD9C CRC64;
KIVGGYECRK NSVPYQVSLN AGYHFCGGSL IDNQWVVSAA HCYKSFIGYS MCIVRIGEHN
IDLSEGSEQY INAAKIIKHP RYSSRNMDND IMLIKLSGPV SLNSYARAVP LPSSCAGAGT
MCLISGWGNT LSNGVNYPSM LQCLNAPILT TTQCQNAYPG MITNNMICIG YLEGGKDSCQ
GDSGGPVVCN GQLQGVVSWG YGCADRNHPG VYTKVCNYVS WIRDTMARLE ASVTNYLTYL
NNKLSDSDCT SQKLNSTVNI HIQSQVYLTV HKQHTYLNKG KCVAGPLKND DKIVGGYECR
KNSVPYQVSL RTFFHYCGGC LIDSQWIVSA AHCADPHHSN STEIQLGEYN FNEHEGSEQN
FKPTKIIRHP GFNPSTLDND IMLIKLSQPA SLNPNVRTSP LPSSCADAGT MCLISGWGKT
VSNRDEYPSR LQCLDAPVLS AKQCNDSLPD LLTNNMFCAG YLEGGKDSCE GDSGGPVVCN
GQLQGVVSWG YGCAMKNFPG VYTKVCNYVS WIRDTMNMKI PPPKKNPWCS IIWQNIQSAM
SFSPSEYKFC SVFHLTDTAK CLTSNKLSVG TLKLTNSMYV KERMNELYST SLHLCTHTHS
LPFNDKIVGG HDCQPYSQPW QASLKFRERE RKREERTLDH DIMLLKLVHP VPVNERVRPV
SLPTGCPVAG TPCVVSGWGN ILSDGVFLPA ILQCVTIPIL SYEECDRSYP GMISSTMVCA
GYLEGGKDAC QGDSGGPMVC NGELHGIVSW GFGCAEPNHP GVYTKVCALL PWIESTIAS
//
