ID H3B4P1_LATCH Unreviewed; 574 AA.
AC H3B4P1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Tripartite motif containing 45 {ECO:0008006|Google:ProtNLM};
GN Name=TRIM45 {ECO:0000313|Ensembl:ENSLACP00000016862.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000016862.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000016862.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC {ECO:0000256|ARBA:ARBA00008518}.
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DR EMBL; AFYH01049552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049553; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049557; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049558; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049559; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01049560; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B4P1; -.
DR Ensembl; ENSLACT00000016981.1; ENSLACP00000016862.1; ENSLACG00000014852.2.
DR GeneTree; ENSGT00940000154334; -.
DR HOGENOM; CLU_013137_14_8_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19809; Bbox1_TRIM45_C-X; 1.
DR CDD; cd19785; Bbox2_TRIM45_C-X; 1.
DR CDD; cd16588; RING-HC_TRIM45_C-VII; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF291; TRIPARTITE MOTIF-CONTAINING PROTEIN 45; 1.
DR Pfam; PF00630; Filamin; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00557; IG_FLMN; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 28..92
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 124..170
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 180..216
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REPEAT 388..491
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT COILED 243..302
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 574 AA; 63418 MW; 912684466D3AA57B CRC64;
LNVVSTPNAG LISSSVRGEM GSPSRTHCPA CGCLYLEPRI LPCLHTLCSS CIRQLEPVSV
PGLRVGDSDS GSEGSWAREQ PCPVSLLCPV CDSEVDLPRD GVDGLVVNQL VVSEVFLLSL
RSQEVDLVCD LCSEGDAERR CEVCNVNLCD FCCKAHRRQK KTASHGTIAL KDLKGSGRIL
RPVLCSLHPP EELKLFCETC DRPVCRDCVV GDHRDHACDF SSAVIHKYGD YVRELLKRTQ
PHLGALEEAL REIERVSQAV EERVETVADE IKAFACSYVK AIEKHRDRLL KQLREMKNHK
ENCLHLQRIQ LEQLLSDMRT GVDFTEHLLT SGSNLEILVT KEVVINRLKR LNEMRYKIHP
GVDDGIWFTP QERAGQCDGF EVQGVILMRA VDPSKSIIQG EGFHVGRQGR ESEFLLVCND
TLGERMGRGG ESVRVSIIHK DNNECIITPV VTDNNNGTYQ ISFIPQEAGI YTVWVCVQGQ
HVQGSPFSLT VKSKFRKHNG MFHCCTFCSS QGQKDARCGC GGTMPGGYQG CGHGHKGHPG
QPHWSCCGKT TENSDCSGSL SANHSRSLLR TVAL
//
