ID H3B6A1_LATCH Unreviewed; 833 AA.
AC H3B6A1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Cell division cycle protein 27 homolog {ECO:0000256|ARBA:ARBA00039307};
GN Name=CDC27 {ECO:0000313|Ensembl:ENSLACP00000017422.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000017422.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000017422.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the APC3/CDC27 family.
CC {ECO:0000256|ARBA:ARBA00038210}.
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DR EMBL; AFYH01058102; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058103; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058104; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058105; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058106; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058107; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058108; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01058110; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005994693.1; XM_005994631.1.
DR AlphaFoldDB; H3B6A1; -.
DR STRING; 7897.ENSLACP00000017422; -.
DR Ensembl; ENSLACT00000017550.1; ENSLACP00000017422.1; ENSLACG00000015346.1.
DR GeneID; 102358952; -.
DR KEGG; lcm:102358952; -.
DR CTD; 996; -.
DR eggNOG; KOG1126; Eukaryota.
DR GeneTree; ENSGT00950000182950; -.
DR HOGENOM; CLU_008850_1_0_1; -.
DR InParanoid; H3B6A1; -.
DR OMA; WHSPQAW; -.
DR OrthoDB; 152021at2759; -.
DR TreeFam; TF101058; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000015346; Expressed in chordate pharynx and 6 other cell types or tissues.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13181; TPR_8; 4.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 569..602
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 603..636
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 637..670
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 671..704
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 739..772
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 336..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 92489 MW; 6D005D0C5C7C5FF3 CRC64;
MTVLQEPVQA AIWQALNHYA YRDAVFLAER LYAEVHSEEA LFLLATCYYR SGKAYKAYRL
LKAHSCTTPQ CKYLLAKCCV DITKLAEGEQ ILAGGVLNKQ KSYDDIVSEF GDSACFTLSL
LGNIYCNTGR LAKGSECYQK SLSLNPFLWS PYESLCEIGE KPDPEQTFKI TSLQNFSTCQ
LNACTTFVSN HNVSHRQPET VLMETPQDTI ELNRLNLESS NSKYSSVSAD SSVSYIDSAV
ISPDSVSLGS GTTILPKQAQ NKPKSGRNLL GCPASFSPLT PSFGILPLET PSPGDGSFLQ
SYTNSSSVVD VPPAGAPSRK SLTRNSVSGT KLVFTQSGNS REVTPVPLAQ TQSTGPQTST
TPQVLSPTIA APPNALPRRS SRLFTSASST AKENSKKLKM KFPPKIPNRK TKSKPSKGGI
TQPNMNDSLE ITKLDSSILS EGKVSTVTPQ IQAFNIQKAA AEGLMTLLRD MGKGYLALCS
YNCKEAINIL SQLPPHHYNT GWVLCQIGRA HFELAEYMQA ERIFSEVRRI ESFRVEGMEI
YSTTLWHLQK DVDLSVLSTD LINLDRSSPE AWCAAGNCFS LQREHDVAIK FFQRAIQVDP
HYAYAYTLLG HEFVLTEELD KALACFRNAI RVNFRHYNAW YGLGMIYYKQ EKFNLAELHF
QKALRINPQS SVLLCHIGVV QHALKKSEKA LDTLNKAINI DSKNPLCKFH KASILFATEK
YKAALQELEE LKQIVPKESL VYFLIGKVYK KLGQTHLALM NFSWAMDLDP KGANNQIKEA
IDKRYLPDDE ECVAQEQISE SFLQESVATD ESQESSMTDA DDTQLLAAGS EEY
//
