ID H3B9J6_LATCH Unreviewed; 181 AA.
AC H3B9J6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Transcription elongation factor A1 {ECO:0000313|Ensembl:ENSLACP00000018567.1};
GN Name=TCEA1 {ECO:0000313|Ensembl:ENSLACP00000018567.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000018567.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000018567.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00649}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFYH01047267; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01047268; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01047269; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01047270; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01047271; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3B9J6; -.
DR STRING; 7897.ENSLACP00000018567; -.
DR Ensembl; ENSLACT00000018700.1; ENSLACP00000018567.1; ENSLACG00000016348.1.
DR eggNOG; KOG1105; Eukaryota.
DR GeneTree; ENSGT00940000155121; -.
DR HOGENOM; CLU_037637_2_1_1; -.
DR InParanoid; H3B9J6; -.
DR OMA; KTIVETH; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000016348; Expressed in pectoral fin and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd00183; TFIIS_I; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035100; TF_IIS-typ.
DR InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR11477:SF1; TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08711; Med26; 1.
DR PIRSF; PIRSF006704; TF_IIS; 1.
DR SMART; SM00509; TFS2N; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 5..82
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT DOMAIN 142..181
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 83..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 181 AA; 20021 MW; 2135648048FEB5D8 CRC64;
MGREEEIIRI AKKMDKMVQK KNPTGALDLL KELKSIPMTL ELLQTTRIGM SVNAIRKQST
EEEVTSLAKS LIKSWKKLLD GPSADKVTEE KKKESFSSSQ NSPEPREESS SSNSSSKNEG
SNSPTNSCIN TYPLAPNTSD SVRLKCRELL AAAFRMDDDY IAIGADCEEL GAQVEEYILS
I
//
