ID H3BCE2_LATCH Unreviewed; 1047 AA.
AC H3BCE2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0000259|PROSITE:PS50067};
GN Name=KIF28 {ECO:0000313|Ensembl:ENSLACP00000019563.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000019563.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000019563.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; AFYH01042735; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042737; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042738; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042741; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BCE2; -.
DR STRING; 7897.ENSLACP00000019563; -.
DR Ensembl; ENSLACT00000019701.1; ENSLACP00000019563.1; ENSLACG00000017202.1.
DR eggNOG; KOG0245; Eukaryota.
DR GeneTree; ENSGT00940000163104; -.
DR HOGENOM; CLU_001485_2_3_1; -.
DR InParanoid; H3BCE2; -.
DR OMA; QVIFERI; -.
DR TreeFam; TF105221; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22709; FHA_KIF28P; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF6; KINESIN-LIKE PROTEIN KIF1C ISOFORM X1; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 11..359
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT COILED 374..436
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 880..914
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 114..121
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1047 AA; 118700 MW; 418A73366E4EFEF9 CRC64;
KGKEKMPNLD SVKVAVRVRP FNQREKDAGS QCVISMNSNC TTICDPRNPE NRKSFTFDIA
YWSHSGFIKN ADGKFIPGGL GSRYADQMKV FNDLGQGVLD NAWQGYNATL LAYGQTGSGK
SYSMIGYGAN RGIIPIVCEE LFRVINNNQD KNKQYQQVSF SMLEIYNEQV KMLISKQCAP
SSLKICVDVF LFLFFGGGKY LKGETEGISK LVTSPATRPM PRTDRLNSPS DSTSMYLAQF
FYKIFLEENI TKQSSINMVD LAGSERQKVS GSEGDRLREG TAVNLSLTTL GNVISSLAEV
AVRKRVLHIP YRDSVLTKLL QSALGGNSRT IMMAALSPAD ICYEETLSTL RYAERAKKIK
NKAVVNKSPT EKLIKELKAE NAKLLSKLAR LGSSGQLHRL LAENELQIQA IQVFWEQHLE
EARREWEQQY AAIAQERRLM QMFPYLLNVN EDPQLSGVIK HFIQDGESEV GQSGTTLNAI
TLKGLGILDK HATFTNTENK VTIEPHGRAK VIVNGVSAVT KTQLRHLDRI ILGSSNTYIY
IGFPNERNNE DLSRFDYDFF QSELAAAEGI NMDKLDPPPP GYHTPPPNVL AMFHDYIKVM
PLVAEANQMS EEPFKQDLKF ELQVKNLALS DSKGHDLEKE IAVKVTNRTN NLVWVWSKAK
FINRKFLMEE LYQRYMEGKD VSVDRVSDPF WDPVEAVHLG SAHVWLQSLA YCIKLEEQVE
FLNSESNEEA MLQINLVPCS RAGEPFGEDD IMIDPSELLG NRLDFQIQIN QCLGLKWLKQ
VRERGVQIGY RVYNCPNTFY MQPVWGNVNP KLHHVMHFTV LNVSQEFLSY LLTNALVVDL
WGLQEGCTEM DCSFQDVRFT EEGSVIIDET KVLLSNNTVI ETNENQLSEL YLKLSKLEKE
MELLRDVNRA LREDNTILKG MLKKPDTEAP EVICSVMKRP PPPLGPKCWE DKQVCLQWSS
DYDAEFAKAL KAFYQSMNSV RGQLVRLRRH RPTKDEGNLQ TLELFMEEQA QMLKDFGEQL
EVCVNKLKND VATIVKKKRD SLGCIKP
//
