ID H3BTA5_HUMAN Unreviewed; 113 AA.
AC H3BTA5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Intraflagellar transport 140 {ECO:0000313|Ensembl:ENSP00000457092.1};
DE Flags: Fragment;
GN Name=IFT140 {ECO:0000313|Ensembl:ENSP00000457092.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000457092.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000457092.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000457092.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL031705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL031719; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL031720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL133297; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z97633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z97652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BTA5; -.
DR SMR; H3BTA5; -.
DR MassIVE; H3BTA5; -.
DR PeptideAtlas; H3BTA5; -.
DR ProteomicsDB; 42580; -.
DR Antibodypedia; 23147; 96 antibodies from 21 providers.
DR Ensembl; ENST00000569812.1; ENSP00000457092.1; ENSG00000187535.14.
DR UCSC; uc059oyy.1; human.
DR HGNC; HGNC:29077; IFT140.
DR VEuPathDB; HostDB:ENSG00000187535; -.
DR GeneTree; ENSGT00940000153417; -.
DR HOGENOM; CLU_171494_0_0_1; -.
DR OMA; DFDLIWN; -.
DR ChiTaRS; IFT140; human.
DR Proteomes; UP000005640; Chromosome 16.
DR Bgee; ENSG00000187535; Expressed in right uterine tube and 136 other cell types or tissues.
DR ExpressionAtlas; H3BTA5; baseline and differential.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR15722; IFT140/172-RELATED; 1.
DR PANTHER; PTHR15722:SF7; INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 1: Evidence at protein level;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Proteomics identification {ECO:0007829|EPD:H3BTA5,
KW ECO:0007829|MaxQB:H3BTA5};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 59..112
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT NON_TER 113
FT /evidence="ECO:0000313|Ensembl:ENSP00000457092.1"
SQ SEQUENCE 113 AA; 12704 MW; C6E380D7ADE612A2 CRC64;
MALYYDHQIE APDAAGSPSF ISWHPVHPFL AVAYISTTST GSVDIYLEQG ECVPDTHVER
PFRVASLCWH PTRLVLAVGW ETGEVTVFNK QDKEQHTMPL THTADITVLR WSP
//
