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Database: UniProt
Entry: H3BWE7_TETNG
LinkDB: H3BWE7_TETNG
Original site: H3BWE7_TETNG 
ID   H3BWE7_TETNG            Unreviewed;      1199 AA.
AC   H3BWE7;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   25-OCT-2017, entry version 37.
DE   SubName: Full=Potassium large conductance calcium-activated channel, subfamily M, alpha member 1a {ECO:0000313|Ensembl:ENSTNIP00000000309};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000000309, ECO:0000313|Proteomes:UP000007303};
RN   [1] {ECO:0000313|Ensembl:ENSTNIP00000000309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A.,
RA   Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B.,
RA   Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S.,
RA   Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B.,
RA   Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V.,
RA   Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J.,
RA   Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S.,
RA   Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J.,
RA   Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M.,
RA   Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C.,
RA   Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals
RT   the early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|Ensembl:ENSTNIP00000000309}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTNIP00000000309}.
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DR   Ensembl; ENSTNIT00000004025; ENSTNIP00000000309; ENSTNIG00000008628.
DR   eggNOG; KOG1420; Eukaryota.
DR   eggNOG; ENOG410YUX1; LUCA.
DR   GeneTree; ENSGT00530000063026; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0060072; F:large conductance calcium-activated potassium channel activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR024939; Ca-act_K_channel_Slo-1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003929; K_chnl_BK_asu.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR10027:SF28; PTHR10027:SF28; 1.
DR   Pfam; PF03493; BK_channel_a; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007303};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     45     67       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    139    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    177    195       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    260    281       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    297    315       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    327    345       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      140    351       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1199 AA;  134947 MW;  8B6AC79FA2C91C03 CRC64;
     SDSSMRTSNI NNNINPDSSI LMSKMEDVVI PYSSMVPCDN NGQRMWWAFL ASSMVTFFGG
     LFIILLWRTL KYLWTVCCHC NIKNKEAQKV NNPTNNQPAE KKKGPDEKEE AAASEVGWMT
     SVKDWAGVMI SAQTLTGRVL VVLVFALSIG ALGIYFIDSS DPIESCQNFY KDFTLQIDMA
     FNVFFLLYFG LRFIAANDKL WFWLEVNSVV DFFTVPPVFV SVYLNRSWLG LRFLRALRLI
     QFSEILQFLN ILKTSNSIKL VNLCSIFIST WLTAAGFIHL VENSGDPWEN FQNSQSLSYW
     ECVYLLMVTM STVGYGDVYA KTTLGRLFMV FFILGGLAMF ASYVPEIIEL IGNRKKYGGS
     YSAVNGRKHI VVCGHITLES VSNFLKDFLH KDRDDVNVEI VFLHNISPNL ELEALFKRHF
     TQVEFYQGSV LNPHDLARVK IESADACLIL ANKYCADPDA EDASNIMRVI SIKNYHPKIR
     IITQMLQYHN KAHLLNIPSW NWKEGDDAIC LAELKAGFIA QSCLAQGLST MLANLFSMRS
     FIEIEEDTWQ KYYLEGVANE MYTEYLSSAF VGLSFPTVCE LCYVKLKLLL IAIEYKSEQR
     ESRTPSILIN PGNHVKMQEG TLGFFIASDA KEVKSIFYYC KACHDDITDP KRIKKCGCKR
     PKMSVYKRMK LACCFDCGRS EQDCSCMSGS VHSNMDTLQR AYPLSSVSVH DCATTLRAFE
     DEHPSTLSPK KKQRNGGMRN SPNCSPKMMS RHDPLLIPGN EQIENMDMNV KRYDSTGMFH
     WCPSKEIEKV ILTRSEASMT VLSGHVVVCI FGDVTSALVG LRNLVMPLRA SNFHFHELKH
     IVFVGSLDYL RREWETLHNF PKVSILPGTP LSRADLRAVN INLCDMCVIL SANQNNIEDA
     SLQDKECILA SLNIKSMQFD DSIGVLQANS QGFTPPGMDR SSPESSPVHG FVRQASVTTG
     SNIPIITELV NDSNVQFLDQ DDDDDPDTEL YLTQPFACGT AFAVSVLDSL MSATYFNDNI
     LTLIRTLVTG GATPELEALL AEENALRGGY STPQTLANRD RCRVAQLALY DGPFADLGDG
     GCYGDLFCKA LKTYNMLCFG IYRLRDAHLS TPSTCTKRYV ITNPPYEFEL VPTDLIFCLM
     QFDHNAGQSR TSLSHSSHSS HSSSKKSSSV HSVPPSNRQN RSSKTREARD KQKKEMVYR
//
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