ID H3BWW5_TETNG Unreviewed; 619 AA.
AC H3BWW5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=ZP domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000000478.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000000478.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; H3BWW5; -.
DR STRING; 99883.ENSTNIP00000000478; -.
DR Ensembl; ENSTNIT00000002851.1; ENSTNIP00000000478.1; ENSTNIG00000014061.1.
DR GeneTree; ENSGT00940000156742; -.
DR InParanoid; H3BWW5; -.
DR OMA; PPECYLA; -.
DR TreeFam; TF330284; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 3.10.250.10; SRCR-like domain; 1.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR PANTHER; PTHR14002:SF40; UROMODULIN; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF00530; SRCR; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00202; SR; 1.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF56487; SRCR-like; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50287; SRCR_2; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..619
FT /note="ZP domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003581592"
FT DOMAIN 78..119
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 310..354
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 352..604
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 619 AA; 68639 MW; 847B65FA1C63D418 CRC64;
MGLPEGVLWL LVLHVLTASA SDFLLRKASE LERARANCDS CHDEAACLET KDRGDAFLTF
SCVCKDGFVG DGLTCYDDVD ECSLPDSPCQ EPQVCQNTQG SYECLLQDAF TDLPGLRCTD
SLEATLQQIC DSCHDEAACL ETKDRGDAFL TFSCVCKDGF VGDGLTCFDC GYGLCPPGMD
CLEGSDGLMG CVDPCENYRT LADDWRAVNY SLDTSHNDKV AFKDWYRLVL WQRSAHIPER
CVAEGRCGTR YPIWTNTPHP VESGVIKTIN TCSHYSGRCC QYATGSIYVK LCYREYYIYK
LKTTGLFEVY CAVNGSGPCV GRVEIFLRGQ WGTVCDDAWD LTDAQPEEHQ LVCGLDKIEL
GFSVAALRAR GLDPFSGHLA VVNCSRFRVQ SGQVWYEVET REGVCGNTLR VNSTHAVYSN
SLFIYFANTT SFFVPKSFPF RCVYPLDTNT SMDVAINPFL EFREGVVGEG ARAEASMFLY
RSSNYSEVYP AGQVTLPVGS PLYVGVSLDQ HVRGFVVVLE DCYASHSPNP DHPTRQYLIQ
NKCPSDRRRV AVTESGLSLR ARFSALLFLI QDQYSNMYLH CSLTLCSPEV SSCVPRCRSR
TSRSVSGSEN LKHLSVGPI
//
