ID H3CRR5_TETNG Unreviewed; 485 AA.
AC H3CRR5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase {ECO:0000313|Ensembl:ENSTNIP00000010949.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000010949.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000010949.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
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DR AlphaFoldDB; H3CRR5; -.
DR STRING; 99883.ENSTNIP00000010949; -.
DR Ensembl; ENSTNIT00000011131.1; ENSTNIP00000010949.1; ENSTNIG00000008124.1.
DR GeneTree; ENSGT00390000008647; -.
DR HOGENOM; CLU_012079_0_0_1; -.
DR InParanoid; H3CRR5; -.
DR OMA; CWLCARI; -.
DR TreeFam; TF314121; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000030; F:mannosyltransferase activity; IEA:InterPro.
DR CDD; cd03816; GT33_ALG1-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR026051; ALG1-like.
DR InterPro; IPR001296; Glyco_trans_1.
DR PANTHER; PTHR13036; BETA1,4 MANNOSYLTRANSFERASE; 1.
DR PANTHER; PTHR13036:SF0; CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 296..450
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
SQ SEQUENCE 485 AA; 55029 MW; B499F063CC9C5483 CRC64;
MAAHSDYLRL FTVFVFILAM FYAAGLTVSW SVVLVIGLFG IMLPLLRRMR QRTSGTSRRV
CVLVLGDIGR SPRMRYHSLS LSKHGFNVTF VGFVETKPPE DLLKEDKIKI VPIREMKGVK
GPKILTYATK VVFQCLQLLS VLMRMELQSH ILMQNPPGLP SISVAWFVSI LRGSRLIIDW
HNYGYSIMAL SHGQGHPVVR LAERYEHFFG PLATHSLCVT NAMKADLQNN WGIRATTLYD
RPASFFRETP LEVQHELFLK LANTHPQFQS SISELEEKNL EKTAFTVRDF THDTVTRRPK
RPALLISSTS WTEDEDFSVL LKALEEYEGF VRGGASLPSL VCVITGKGPQ KDHYRRLIAS
LHLQHVNICT PWLEAEDYPV LLGSADLGVC HTSSSGLDLP MKVVDMFGCC LPVCAIHFSC
LHELVKHEEN GLIFRDFQEL AEQLKSLLSE FPSSESKLGM FRRNLRISRG QCWDDNWDQI
VLPLI
//
