ID H3CYX6_TETNG Unreviewed; 323 AA.
AC H3CYX6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Sidoreflexin {ECO:0000256|RuleBase:RU362000};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000013461.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000013461.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC membrane {ECO:0000256|RuleBase:RU362000}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU362000}.
CC -!- SIMILARITY: Belongs to the sideroflexin family.
CC {ECO:0000256|ARBA:ARBA00005974, ECO:0000256|RuleBase:RU362000}.
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DR AlphaFoldDB; H3CYX6; -.
DR STRING; 99883.ENSTNIP00000013461; -.
DR Ensembl; ENSTNIT00000013655.1; ENSTNIP00000013461.1; ENSTNIG00000010549.1.
DR GeneTree; ENSGT01030000234641; -.
DR HOGENOM; CLU_039425_2_1_1; -.
DR InParanoid; H3CYX6; -.
DR OMA; AVMRQSE; -.
DR TreeFam; TF313205; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004686; Mtc.
DR NCBIfam; TIGR00798; mtc; 1.
DR PANTHER; PTHR11153; SIDEROFLEXIN; 1.
DR PANTHER; PTHR11153:SF17; SIDEROFLEXIN-5; 1.
DR Pfam; PF03820; SFXNs; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362000};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU362000};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362000};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362000}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 95..122
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
FT TRANSMEM 147..168
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
FT TRANSMEM 240..257
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
FT TRANSMEM 269..293
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362000"
SQ SEQUENCE 323 AA; 35298 MW; 574CCEE63EA3D6B4 CRC64;
NMSQYPAFAL GKSRFDQSTF SGRLRHFLDV IDPSTLFVTE KRLQESVELL HRFKQGSLPA
GVTDAQLWQA QKVKQAIIHP DTGEKILMPF RMSGFIPFGT PVVVGLLLPN QSLLSAVFWQ
ALNQSHNACF NYCNRNASQP APFSRFFQGY VGAVTSAVSI AVGLKVLVQK ARRFSPTTRL
LVERFIPFPA VATANVCNVV LMRHSELSEG ISVLDDNGNV VGTSKVAARH ALLETALTRV
VMPVPILVLP PIVMSALEKL PLLQRQPRLV LPVHAAVCLA AFSLALPVAV SLFPQTSQIG
TKQLEPEIAM ATDCTIVTYN KGL
//
