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Database: UniProt
Entry: H3CZW3_TETNG
LinkDB: H3CZW3_TETNG
Original site: H3CZW3_TETNG 
ID   H3CZW3_TETNG            Unreviewed;       845 AA.
AC   H3CZW3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   22-NOV-2017, entry version 35.
DE   SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2a {ECO:0000313|Ensembl:ENSTNIP00000013799};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000013799, ECO:0000313|Proteomes:UP000007303};
RN   [1] {ECO:0000313|Ensembl:ENSTNIP00000013799}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A.,
RA   Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B.,
RA   Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S.,
RA   Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B.,
RA   Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V.,
RA   Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J.,
RA   Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S.,
RA   Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J.,
RA   Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M.,
RA   Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C.,
RA   Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals
RT   the early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|Ensembl:ENSTNIP00000013799}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTNIP00000013799}.
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DR   STRING; 99883.ENSTNIP00000013799; -.
DR   Ensembl; ENSTNIT00000013994; ENSTNIP00000013799; ENSTNIG00000010870.
DR   eggNOG; KOG1419; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00550000074513; -.
DR   OMA; VPKTWNG; -.
DR   OrthoDB; EOG091G02ZT; -.
DR   TreeFam; TF315186; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR020969; Ankyrin-G_BS.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR003947; K_chnl_volt-dep_KCNQ2.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   PANTHER; PTHR11537:SF6; PTHR11537:SF6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   Pfam; PF11956; KCNQC3-Ank-G_bd; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01461; KCNQ2CHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007303};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     95    115       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    127    148       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    169    187       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    253       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    295    320       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      106    320       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      440    627       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   845 AA;  94297 MW;  27DEACCA3C025418 CRC64;
     MVQKSLNGGV YPEEEGEKKH KVGFVGLDPG APESSRDGAL LIAGPDGAHK RSSILCRRGS
     GVSTGRPRPS KKNASYRKLQ NFLYNALERP RGWAFVYHAY VGLLVLLCDF LDVSATIKEF
     KNSSESALYI LEIVTIVVFG VEYIVRIWSA GCCCRYRGWR GRLKFARKPF CVIDIMVLIA
     SVSVLAAGSQ GNIFATSAIR SLRFLQILRM LRMDRRAGTW KLLGSVVYAH SKELITAWYI
     GFLCLILASF LVYSVEKESN EEFETYADAL WWGLITLTTI GYGDKVPKTW NGRMLGAAFS
     MIGVAFFALP AGILGSGFAL KVQEQHRQKH FEKRRNPAAC LIQGAWRFYA TNLSRTDLLC
     TWDFYEQTVS VPMYRGFSFS FFVFRFIPPL NQLDLLRNLK GKSFRKESQT ELSPSRKASL
     KDKVFPSPSK APFAKGKAPS PGAEDGVETS PYKVAKSWSF NEKNRGAKNS LKARGSSSRQ
     NSEEASLPGE EVGDDKSCHC DFLTQELPSS LKVTIRAVCI MKFLVSKRKF KESLRPYDVM
     DVIEQYSAGH LDMLCRIKNL QTRIDMIVGP PPPSTPRHKK STEGPRDGEA GDDLSMMGRL
     VKVEKQVLCM DRKLDFLVNV YVQRMGITHS ETEAYFNSKE PYPAPPYHSP DESKLEKDPK
     EQMNSLEQKD PLLGRSVARS LGSPSASQSR PSTSWQHQLQ HPLSQPAWNS SVANTPSPVC
     GDRSPNLFRL PPPPAPAHDR SSGSSSQSRR RRRRQTCQQA ESDTSLSIPS VDHEELERSF
     SGFSISQAKE DFFGASFFAG PPVCPRDRPF IAEGESDTDS DLYAPSPVSF TGDIFCGEKP
     WPGLK
//
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