ID H3D2U8_TETNG Unreviewed; 2064 AA.
AC H3D2U8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTNIP00000014836.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000014836.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000014836.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR Ensembl; ENSTNIT00000015037.1; ENSTNIP00000014836.1; ENSTNIG00000011878.1.
DR GeneTree; ENSGT00630000089884; -.
DR HOGENOM; CLU_001610_0_0_1; -.
DR InParanoid; H3D2U8; -.
DR OMA; HRKTTGV; -.
DR TreeFam; TF329577; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031248; RNF213.
DR InterPro; IPR046439; ZF_RZ_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22605:SF21; E3 UBIQUITIN-PROTEIN LIGASE RNF213-BETA; 1.
DR PANTHER; PTHR22605; UNCHARACTERIZED; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR Pfam; PF20173; ZnF_RZ-type; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS51981; ZF_RZ; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 866..904
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 1347..1419
FT /note="RZ-type"
FT /evidence="ECO:0000259|PROSITE:PS51981"
SQ SEQUENCE 2064 AA; 233070 MW; 5FE144FA578A9A81 CRC64;
METGRTVILL NMQNLYESLY DALNQYYVYL GKQQYVDLGL GSHRVKCRVH SNFKLVVAED
QKKVYEQFPV PLINRLEKHR LDRSTDLEPW QHRVLHKLTE WVKEFSGVAL KRFSLSDIFI
GYHDDACGSA LLQALERRAQ KTEDSVLSQQ KEAKCLLLNC ATPDAMVRLR CSDLTKQEVQ
KLQRIYFQQQ HHQSFQDFLQ FHLNSCQSTS RFFEITTFSS LLTRSDIRPI SQALQVDTEK
ILLLSLHQFD TEASFCNKLR SFLQNADHSL QILLIQMDLE ESHCSDELIA SAKFCTMNSL
MSLDGHTCWV VFIVKVSRFQ SHCRYLGFQG GVWHSVHIDD LRNPKDMSSD LFRLCGTLIS
TLLCPAPPDC LNLLNIILTE HNEDGEMRSG DIQNCFVALV QAEGALHSLS LVRSCVQKAA
GLLRDNCGVA SRSVQRINIL LTLLGAAGGQ TGAYFQEVLL ARLVEAIKKK EEMIDSPKDW
VSTQAKNQQA LQEGGTLRHT LWRHLQCVVT PFLANIFEVM DRFANLDLLA EGKLSPGLEK
LWLNILADSQ ILVLTVSQKS SEADQEVLVL DGEEHHCAAP FSWLVTLHLE SLWEESEFIP
EGDEGRILQF VSLFNNSRLG HLFQTLSAED RIEYGRNYLQ DFLLLSLKIK SKDKLMVFFR
AMLGCVSELQ ASLGVISDLS PAWIMAAARR FDPRLDTLNH VLLLQPQLAA DIRRQWSQTE
PNEMTEDILA LGVCIEQTKL LTVTSLQECE RFVSRVEFLQ PCLERAFSQK YSSLCSPGCS
QELGSIRSLW HGILMVASFI QHIIFKLKQS DSRLKKAGLK HCSILLHLMR ESPDVKSAVT
LEQLIRILNS LHDECISGEL RFGISCTVCL EELTEPSVLP CQHVTCLTCL QRCLVWRHSC
PVCRVALPPT FQPTVSPTIK AALQQQSDVR GYCNGFFLEV VSRFCLSEGQ QPAEGVVELL
FSLLVFASGL WCHAGDTYRT RELTPFLECM DNSPVVRSVL PKLLMQYSFD QVKVYIQTYL
KNLEENLLSP EDSTQLHLLF VSCFQDSLLC SEARELESKD QYRKAEIHFL SRMARKQTPD
RREEPAEFLL NTAKLRICLS SAALQLKKAA DQGKDDVDIQ YMQQVKAVCE YSGNDWYRIY
LLRAVYRLSG VDCVLYLMNN PSWSWVFPPD LLRLQVTEER MCPEKMDRFL CCGTSYQGVR
HAVTRFILET RTEDMVTEMK TLNCKKLRGS QVSLLALALF RQVTCRYKSC DADRLLSQQE
TTRLEELLQG ICLVDYRDFC AALLSNQVGG AGSSLRVVQG LSIQRQTLLE LLVHLGSVLL
TGNHLLTPLR NIAFQPHTVT NFFLPTMADD HTSKARGWLG SENVRMYYCA KGHACFVGEC
GRPVVVSRCP DCGNPIGGIN HNPVQGFSQT TSGEDQTRTG HILGEAAQRS DAAERQMTCA
QTCILRLLTH LAMLLGSIKD QRSVGDMIHP RCSDVSSFLW SHLEKDIHVL GEALGQNLDN
TAIAVHLILR ICADSECRSG SRDGGLNLST PQSRQEWERL VCDSAISPVL HNLQQKLAEA
QRRITADDGL VGSPVMKTLL GDPASMLSLP AGCPTHCSSF WNLPENVTVK SFSQLVEQSP
DHSSLDLLIT FLQKINCVKQ LHHLPELAAL QSDLLRIGSL ISDCRAQSIA QVLQNIPAGC
QKKMLVGRVE RFITVWNSLR ADVANNAADL GVEVWLCEME MTKESCGEFL APSRHGPGSC
LRILVELLLK TQNSLVREAR TLRGQDDREY VVPLERVSES QLVLCHPERE LLPLVLSHCH
YTLKKGGETH SSYDLPAIQM QLVRRYLAGK PLIKELQGTE RYLNRHLQDF SVVLAEVRGN
IRQAPLKGSV CAAVRTVLRS YTDVCDAIFV LEIGLRFLAK TGGDPQGHLL SFLTESLQLD
SQISSTVAKS LGESRLKHSV FTWQLLTCWR SELMLKRKQE PFQRLPSQFQ QKLSEVERRG
LRQFLAVTDV DAFALELHEV LLLKTSNAVP EEGYQAHWDI RSTLENHLDQ KELPPLLGLE
VLPEEITLGQ GPDVWRAAME FKRR
//
