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Database: UniProt
Entry: H3D8B0_TETNG
LinkDB: H3D8B0_TETNG
Original site: H3D8B0_TETNG 
ID   H3D8B0_TETNG            Unreviewed;      1647 AA.
AC   H3D8B0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   25-OCT-2017, entry version 37.
DE   SubName: Full=Sodium channel, voltage-gated, type IV, alpha, b {ECO:0000313|Ensembl:ENSTNIP00000016751};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000016751, ECO:0000313|Proteomes:UP000007303};
RN   [1] {ECO:0000313|Ensembl:ENSTNIP00000016751}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A.,
RA   Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B.,
RA   Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S.,
RA   Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B.,
RA   Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V.,
RA   Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J.,
RA   Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S.,
RA   Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J.,
RA   Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M.,
RA   Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C.,
RA   Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals
RT   the early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|Ensembl:ENSTNIP00000016751}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTNIP00000016751}.
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DR   Ensembl; ENSTNIT00000016965; ENSTNIP00000016751; ENSTNIG00000013749.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   GeneTree; ENSGT00830000128242; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028809; Na_channel_a10su.
DR   PANTHER; PTHR10037:SF208; PTHR10037:SF208; 3.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007303};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    124    147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    243    265       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    388    414       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    560    580       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    592    613       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    634    662       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    682    701       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    758    781       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    943    965       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    971    996       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1008   1029       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1061   1080       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1174   1193       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1254   1272       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1284   1306       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1318   1341       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1386   1412       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1424   1446       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1476   1498       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      128    414       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      563    785       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      943   1203       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1253   1508       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1647 AA;  188579 MW;  BCAAB311A3F07D06 CRC64;
     LASLLPPVGT EFLRPFTSAS LEQMSQRKEE EKKQKGKKKD QKVKNNELPK PSEDLEEGKP
     LPFIFGEPSP AHLNTPLEEL DPHQSEVSTF LVLGKGKLIH RFNAHKACCL FGPLNPLRTL
     AIKILTNTLF SSLIFVTILI NFVLTVVSTD FYAMSKIVEL SFTAVYLLEV VVKIVSRGFC
     WGKFTFLRNP WNWPDVGVIA GAYEALFVDF PELKMVSLVL KTFPIFQGLK KTLSSFVQAM
     KRLSCVLALT AFMLCILSII GQLLFQGSLR QKCISWPEAD HNLTSHSFIS HYDDDQSSDF
     NYYEHVNNPN NSYIPSGMTD ALVCGNTSNA GACPTGFTCL RNQKNPNYGY TSFDSFGWAL
     LSSFRLLTQA YWDDLMRLVL RANGKTSFIY FLFLLSPCWF VLVSLMAAVM AAALCERERT
     RLAEASRKEK EFNQIVKALR KRGGEEAKSD FCVPSLLLEF KQCTDKPLYR YSRRWHSQRV
     PTTTARKAKS HNQPAKEVRK RRSFRLKPDP RRSVHLKACC DPTSILTLSC CPCCSACAKL
     LLTWNCCGCW RWLKRWLHTI VTNPFFDLAI VVCLIINIIF TSMEHFPMTY EFAETLIVAE
     LIFIFIYIGE MLLKILAMDP YNYFKVGWNV YESLIVVLSL FEMVLAEVHG LCILVSVTLL
     RFFRLARWWH EFHVFLKTTL KYSFLLLIVF FGFVAVGYQL FNMPYMVSVC KISEDCSLPR
     WNMNSFFQTF NSIFKMLFDS WVEILWDCME VASPAMCLTF VVSVVVIGNL LILHLFLLML
     LNPYSSDIVA LEERKKNNVE IALGLCKTWI LENICPSLGR KGTKSNQTAS NGQEKKKKDY
     VSLNMATSDE AKVRTPEEEG PEHAKKRHGR RSTGCLLQRP HEQKDSEVLR EKNDEDQKED
     VPESCCCQSC YRCCPVLDVD TSEGAGRCCF SCRKVCLIIV QNFFKLFINV IILLSSTALA
     CEDIYLQHRK VLMAVLAIAE LVFALLFFME MLLKWVGFGF RKYFTDAWCW LEFLIVGVFL
     LSLVGVGSLE TLRVLRVVRI LSFLQGSQRV VGTLFRMVPS LVSGTLVILL VWLVFSVVGV
     QMFAGKFYYC VNETSGEMFH SDVVSNKSEC FELTFSNYTE VRWVNPAINY DNVMMGFLSL
     FILGFSKSWF DIIYSAMDSS LVENQPVYEN NPYVWLYFVF FFIAVFFSLN FFIKVLLTGL
     QKLYFGDQRL FMTQHQQKCS RALMKLFPRS PCRAVPRPQN KCQAGVFDVM NTSCYEIVMA
     ALICLNVLLL VLETVDTTET MYTALHWIYF IFIIIFLLEC IFKLVAFRQH YFKDGWNILD
     FVVVLLQILV LFIEDLVWFY LWPLLGISPD TLAFLRLFRV CRVLHVIPVT RRIRKVLLAF
     LKSVPALFNI AFVLLVVMVV FSLIGMFNFA YVKKAALIDD VFNFETFCSS MICLFMTSTS
     AGWGSLLRPF MNSPPDCDPF AEHPGSDVVG DCSTPIAGVA FFASYIILSF LLLIQLYITV
     VMEIINSEDT ETLCDDDLQN FCKTWMTFDP DDTQLIPYSK LSEFSDSLQD PLRIPKPNAT
     RLVHMDLPLY PGDKVHCTDV FLALAKQVLD DAEGVKSLQA RLEKLLKANS SKVPDEPVSS
     TLRRKQEDTA AKVIQRAFRR RHLRRRS
//
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