ID H3D8Y0_TETNG Unreviewed; 782 AA.
AC H3D8Y0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000016971.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000016971.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in ER-Golgi transport.
CC {ECO:0000256|ARBA:ARBA00002090}.
CC -!- SIMILARITY: Belongs to the COG3 family.
CC {ECO:0000256|ARBA:ARBA00009936}.
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DR AlphaFoldDB; H3D8Y0; -.
DR STRING; 99883.ENSTNIP00000016971; -.
DR Ensembl; ENSTNIT00000017185.1; ENSTNIP00000016971.1; ENSTNIG00000013964.1.
DR GeneTree; ENSGT00390000015682; -.
DR HOGENOM; CLU_011639_1_1_1; -.
DR InParanoid; H3D8Y0; -.
DR OMA; DEFELWG; -.
DR TreeFam; TF314200; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR InterPro; IPR048685; COG3_C.
DR InterPro; IPR048320; COG3_N.
DR InterPro; IPR007265; COG_su3.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR Pfam; PF20671; COG3_C; 1.
DR Pfam; PF04136; COG3_N; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 130..272
FT /note="Conserved oligomeric Golgi complex subunit 3 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04136"
FT DOMAIN 293..637
FT /note="Conserved oligomeric Golgi complex subunit 3 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20671"
FT REGION 504..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 782 AA; 89822 MW; 69EBCAD0EBAA3778 CRC64;
AMASTEHCYL DQTDKDTWEK LSLWDHCTDA LAPLTEKQMD SVLELRSAAE TVSIPSELPI
EDLCSLSSRS LQSPFTATVP ASTEDVLLKG FQMLTMENDR IETAQQFFSW FAKLQTKMDQ
DENVKYRQTR DDLYCYQEQC DAILKDVSAA LEHLDSLQKQ YLFVSNKTGT LHEACEQLLK
EQSELVDLAE SIQQKLSYFN ELENINTKLN SPVLSVNSEG FIPMLSKLDD CIEYVSSHPN
FKDYPVYLTK FKQCLSKAMH FMKVHIVNTM QNLTSQLIKR DPMNLTSADN AFTLYYVKYR
AAAPKVRSLI EQIEERAEKI PEYHRLLDEI HQCYLDQREQ LLRPSITSTI TDLTNQNCKD
HCALVRSGCA FMVHVCQDEH QLYNEFFSKA TSKLDELLEK LCLSLYDVLR PLIIHIIHLE
TLSELCSILK NEMLEDHVQN NTAQLGAFDA VVKQMLEDVQ ERLVYRTHIY IQTDITGYKP
APGDLAYPEK LEMMERIAQS LKEEQMKSQE STFSDIRLED PTGRRNSNPA NVEASSPQAS
ISPADLHGMW YPTVRRTLVC LSKLYRCIDR AVFQGLSQEA LSACIQSLLK ASDIILKNKT
QIDGQLFLIK HLLIMREQIA PFHTDFAIKE ISLDLKKTRD AAFKILNPKA VPKFFRLNSH
NAILEFLLEG TPEIKEHYID SKKDVDRHLK FSCEQFIQQQ TQIFVGNLEE FLTRVAALKT
MAIEGGPTYR LSQQPWAQPA KINDLVTATY RVMKSKLPST LQSMSLYLAN RDTEFILFKP
VR
//
