ID H3DGH5_TETNG Unreviewed; 487 AA.
AC H3DGH5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Suppressor of fused homolog {ECO:0000256|PIRNR:PIRNR011844};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000019619.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000019619.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR011844}.
CC Nucleus {ECO:0000256|PIRNR:PIRNR011844}.
CC -!- SIMILARITY: Belongs to the SUFU family.
CC {ECO:0000256|PIRNR:PIRNR011844}.
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DR AlphaFoldDB; H3DGH5; -.
DR STRING; 99883.ENSTNIP00000019619; -.
DR Ensembl; ENSTNIT00000019849.1; ENSTNIP00000019619.1; ENSTNIG00000016519.1.
DR GeneTree; ENSGT00390000009747; -.
DR HOGENOM; CLU_033906_0_0_1; -.
DR InParanoid; H3DGH5; -.
DR OMA; CQIVGVT; -.
DR TreeFam; TF324548; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.1360.230; Sufu, C-terminal domain; 1.
DR InterPro; IPR020941; SUFU-like_domain.
DR InterPro; IPR024314; SUFU_C.
DR InterPro; IPR038489; SUFU_C_sf.
DR InterPro; IPR037181; SUFU_N.
DR InterPro; IPR007768; Suppressor_of_fused.
DR InterPro; IPR016591; Suppressor_of_fused_euk.
DR PANTHER; PTHR10928; SUPPRESSOR OF FUSED; 1.
DR PANTHER; PTHR10928:SF2; SUPPRESSOR OF FUSED HOMOLOG; 1.
DR Pfam; PF05076; SUFU; 1.
DR Pfam; PF12470; SUFU_C; 1.
DR PIRSF; PIRSF011844; Suppressor_of_fused_protein; 1.
DR SUPFAM; SSF103359; Suppressor of Fused, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR011844};
KW Nucleus {ECO:0000256|PIRNR:PIRNR011844};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 53..229
FT /note="Suppressor of fused-like"
FT /evidence="ECO:0000259|Pfam:PF05076"
FT DOMAIN 243..476
FT /note="Suppressor of fused C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12470"
FT REGION 267..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 54574 MW; C8A8ED5B50D0D7DA CRC64;
MDEARPTSGS QAHGLSPLFP PGLQAIYAEC RRLYPDQANP LQVTAIVKYW LGGPDPLDYI
SMYRNVGCSA QDVQEHWHYV SFGLSDLYGD NRVHEFTGSD GPSGFGFELT FRLKREAGET
APPTWPAELM QGLARYVFQS ENTFCSGDHV SWHSPLDNSE SRIQHMLLTE DPQMQPIQTP
FGTVAFLQIV GVCTEELQAA QQWNGQGILE LMRGVRVAGG PWLITDMRRG ETIFDIDPHL
QQERVDQGIE TEGSNLSGVS AKCVWDDLSR PPEDEEDSRS ICIGSQPRRL SDKVTDTEQI
RETLRKGLEF NPKAALPPIS SQRQSQERPP VSAVPHTPGR LLSRSRKDSL ESDSSAAIIP
HELVRTRQLE SVHLKFNQES GTLLPLCLRG RLLHGRHFTY KSIHGDSAIT FVSSGVEGAF
ATEEHPYAAH GPWLQILLTE EFVEQMLGDI QELNTRDETK LPKEYNWPEK KLKISVLPDS
VFDNPLP
//
