ID H3DH95_TETNG Unreviewed; 732 AA.
AC H3DH95;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Kelch-like family member 4 {ECO:0000313|Ensembl:ENSTNIP00000019889.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000019889.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000019889.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3DH95; -.
DR STRING; 99883.ENSTNIP00000019889; -.
DR Ensembl; ENSTNIT00000020119.1; ENSTNIP00000019889.1; ENSTNIG00000016776.1.
DR GeneTree; ENSGT00940000159818; -.
DR InParanoid; H3DH95; -.
DR OMA; RTGHQSW; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR CDD; cd18336; BTB_POZ_KLHL4; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF26; BTB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 193..260
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 55..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..72
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 81230 MW; D4921B197C197D35 CRC64;
MSVSGKKEFD VKQILRLRWR WFSHSSQGSA GSGGGGIGGV GGYIQQDGLD HRGTPVQGRL
KSHSRERVGL RKTNSPAHSI LAPAPGPTAV CVRAGQQSWH HQQEDIQGLQ VKDDSSKSCS
SPSSKKKENV NTGQEAEKNR TEEPAEMEAR ERLALSNFSR MNTNSSDEFF QATDHAEQTF
RKMETYLQHK QLCDVLLIAG DHKIPAHRLV LSAVSDYFAA MFTSDVKEAK QEEIKMEGVD
PEALRSLVHF AYTGVLELKE ETIESLLAAA CLLQLSQVIQ VCCNFLMKQL HPSNCLGIRS
FADAQGCVDL LNVAHNYTMG HFLEVIQNQE FLLLPTAEIV KLLSSDDINV PDEETIFQAL
MMWVRYDIQN RQQDLGLLLA FIRLPLLPPQ LLADLENNKM FSNDLECQKL LMEAMKYHLL
PERRPMFQSP RTKPRKSTVG ALYAVGGMDA TKGSTTIEKY DLRTNTWVQV GAMNGRRLQF
GVAVIDNKLY VVGGRDGLKT SNMVESYNPL NNVWSTMPPM STHRHGLGIA VLEGPMYAVG
GHDGWSYLNT VERWDPQARQ WNYVASMSTP RSTMGVTALN GKLYAVGGRD GSSCLRSVEC
FDPHTNKWSM CAPMSKRRGG VGVATYNNFL YAVGGHDAPA SNHFLDLRRG ETCDCRYDPK
TDMWTTVSSL SVSRDAVGVC LLGDRLYAVG GYDGQSYLNT VESYDAQNNE WTEEVPLNIG
RAGACVVVVK LP
//
