ID H3DNQ8_TETNG Unreviewed; 289 AA.
AC H3DNQ8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=F-box/SPRY domain-containing protein 1 {ECO:0000256|ARBA:ARBA00016614};
DE AltName: Full=F-box only protein 45 {ECO:0000256|ARBA:ARBA00029979};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000022157.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000022157.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the FBXO45/Fsn family.
CC {ECO:0000256|ARBA:ARBA00007328}.
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DR AlphaFoldDB; H3DNQ8; -.
DR STRING; 99883.ENSTNIP00000022157; -.
DR Ensembl; ENSTNIT00000022395.1; ENSTNIP00000022157.1; ENSTNIG00000018969.1.
DR GeneTree; ENSGT01030000234629; -.
DR HOGENOM; CLU_046756_1_0_1; -.
DR InParanoid; H3DNQ8; -.
DR OMA; DACRGKI; -.
DR TreeFam; TF312822; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd22111; F-box_FBXO45; 1.
DR CDD; cd12907; SPRY_Fbox; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035784; SPRY_FBXO45.
DR PANTHER; PTHR12245:SF7; F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 38..86
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 86..287
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 289 AA; 31025 MW; 5445CA0DBC610518 CRC64;
VMSAGAAGGA GSPCLGAAAG ASCSSAGSFY AAVSGGGAGV AGRLPARVLE HIFSYLELAD
LMRCALVCWH WNSILADENS EVWRSLCSRS LSEEALRSDI LCNLPTYRGK LKAFQHGLSS
NCSRNVYVKK NGFTLHRNPI AQSTDGARGK IGFSEGRHAW EIWWEGPLGT VAVIGIATKR
APMQCQGYVA LLGSDDQSWG WNLVDNNLLH NGEVNGNYPQ CNNAPKYQIG ERIRVILDMD
DKTLAFERGF EFLGVAFRGL PKACLFPAVS AVYGNTEVTM VYLGNPLDG
//
