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Database: UniProt
Entry: H3E6W2_PRIPA
LinkDB: H3E6W2_PRIPA
Original site: H3E6W2_PRIPA 
ID   H3E6W2_PRIPA            Unreviewed;      2645 AA.
AC   H3E6W2;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   10-MAY-2017, entry version 28.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:PPA05445};
GN   Name=WBGene00094999 {ECO:0000313|EnsemblMetazoa:PPA05445};
OS   Pristionchus pacificus (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Diplogasterida;
OC   Neodiplogasteridae; Pristionchus.
OX   NCBI_TaxID=54126 {ECO:0000313|EnsemblMetazoa:PPA05445};
RN   [1] {ECO:0000313|EnsemblMetazoa:PPA05445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PS312 {ECO:0000313|EnsemblMetazoa:PPA05445};
RX   PubMed=18806794; DOI=10.1038/ng.227;
RA   Dieterich C., Clifton S.W., Schuster L.N., Chinwalla A.,
RA   Delehaunty K., Dinkelacker I., Fulton L., Fulton R., Godfrey J.,
RA   Minx P., Mitreva M., Roeseler W., Tian H., Witte H., Yang S.P.,
RA   Wilson R.K., Sommer R.J.;
RT   "The Pristionchus pacificus genome provides a unique perspective on
RT   nematode lifestyle and parasitism.";
RL   Nat. Genet. 40:1193-1198(2008).
RN   [2] {ECO:0000313|EnsemblMetazoa:PPA05445}
RP   IDENTIFICATION.
RC   STRAIN=PS312 {ECO:0000313|EnsemblMetazoa:PPA05445};
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   STRING; 54126.PPA05445; -.
DR   EnsemblMetazoa; PPA05445; PPA05445; PPA05445.
DR   eggNOG; KOG2243; Eukaryota.
DR   eggNOG; ENOG410YCNW; LUCA.
DR   InParanoid; H3E6W2; -.
DR   OMA; ENETHEE; -.
DR   OrthoDB; EOG091G00T0; -.
DR   Proteomes; UP000005239; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IBA:GO_Central.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 1.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS50919; MIR; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005239}.
FT   DOMAIN        1     22       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       28     85       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       93    151       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      331    552       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      765    963       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   2645 AA;  298734 MW;  8513D8B9704E0A43 CRC64;
     MVIYEGGSAV TQARSLWRIE PIRTKWHGAL MGWEQVFRVR HITSGRYLGV VENAVQLYHK
     DKADYDLTAF VMCQNKDPKK QMLDEKEEEG MGTASIVYGE TNVFLQHVKT QLWLSYQTNE
     VTKKGLGKVE EKKAVALKDG HMDDCYTFFM ALEQESKSAR VIRKCSSVLN RFLKGIEALQ
     FEGNQSAIWQ KVDLKEVLKL MEDLIEFFAQ PSDDQDFEDK QNHLRTLRSR QDLFQEEGVL
     NMILDTIDKF SQMEAMPDFA GIIGEENHEK WEQISTYLYL LVAAMIKGNH YNCAQFAAAA
     RLDWLFGRLS NPQSAEGILD VLYCVLTESP EALNMINEGH IRSVIALLEK VGRDPKVLDV
     LSSLCEGNGM AVRSSQNLIT QHLLPRKDLL LQTKMKDHVS SVMPNVLVGV VEGSSLFRKW
     YFEAEVEHVE TMTKEEPYLR VGWANSVGFK PFPGSGDRWG CNGVGDDFYS YGFDGQNAYY
     AGKAKKISQR TLRKGDVVGC ALDLTVPEIR FTLNGQQLAA VFKNFNTDGY FFPVMSLSAK
     VSCRFIFGGT EGRLRHGPPN SFSAIFEAAT DKIDIYECLS FGDVSKSIYG GPQRIISHVD
     PFVPVPIDIS SVSLPHFAME AHTKFAENLH ELWAQRKIEM GWSFGEVRNE QARRHPCLTT
     FQRLPETERR YNLQLALDTI KTIEALGYHI IFDEPPIRVR PVRLPPTYQQ SNQYKPQPLD
     THEIQLGEEM EPLIEALAKN THNIWASEKI KRGWTFGVNE SVDPSQKRSP HLVPYDMVDV
     RIKEANRESA AENIKSLQLF GLFLEVPASE HDEAAVREMA TRRDNTRTYR AEATYAVNGG
     KWYFEFELIT AGFMKIGWMD IAASPDCQLG NDDRSYAFDG FLARKWHQGA ETYGKEWKIG
     DVIGCFLDLN DRTIAFSLNG ELLLDPSGSE MAFDNVMIGE GLVPAMTLGS GQRCKLNFGQ
     DSNSLKFFTT CGLQEGYEPF CVNMYRPMPM WFAKHLARFE DIASSDSVLE VSRIPATGMS
     PPCLKLTQKA TTSEGSNVEK SKMEYIRLSL PVRCHDQFVR NKDKESVLRQ LKEYKPPRSG
     SIAPGYKTIG IPKEFESDNK KNLWETCLDR SISRTLLSAF RQGSEGSDEE VSNRSKQASF
     DEAGEYVTGD AVVSQRQRIA TLMSFGVSSW EASVYTWLRD ENENHEEVLT SVRESLLDMP
     HDERTVAEDH LRELMERERP TKKSGILGRL RDVSHSRQKN RDSKEREGIV RPGSLRQAKN
     NSRSFDAGAI EADIQIGSGG KDVLAPTNPE MPSSGPGRQA TIKHKGSMKK KKTKKETVVV
     ETGKRQSMVP VETMPDGTPV EQDTNALIAL KDKVDEYYYG VRIFPGQDPA NVWVGWVTPH
     VEYRGCYVVN AAELLKEISD AGSTKVTGTL IGCVIDTSIG ELTFQAAGQD TGVKFKLEPG
     AMLFPAAFVT PTAQEVLQFE LGRIKYTFPL SAAMFASMHK STVLSCPPRL TVERLMPIYW
     GRVPNETLRT TSLKLSEARG WSVLCDDPVR IMAVYVPEKD VAFDVLEMIE QPEFLPFHKQ
     TMDLYCKLAS HGNHKVAHTL CHHVTEDQIM YAVMSHSLAG PLRQGFHDLL ISIHLSSHAA
     ARESMAKEYI MAEAYTMTPV MVSDQVREVE MAMSRKEDDM KLLPPSIDLA VLKAHVVSSM
     TMVEGEARIA PLCKATKHAV MNCRDLIGGT NLNHFEPLLK LFDALLVIGL IDNDEIEQVL
     KLIHPVAFDE AYETGTTQKG LTEIELSEGV RLQLVSILDH FCDIQLRHRV VSLVSFAEGF
     VAELQMDQCR RYMDIKQTDM PPAEAARRTK EFRCPPREQM FRLLQCKKKE EKETLLDDDV
     EYDACPMHET LQENLRDFCN LLTQRIGCKD EEEEEEAVME LDDGSSWVDK LARLFVKVPP
     PIVEDDSMFA KGTENFRSYE AYYDRATFFF RKMIIETLRK WATESFIESS DLIRKMFRLL
     LRQYSGVREL RDAMAQTYVL HERNVQDVAD FIVYLIQIRE LLTVQFEATE EAILKRGLWK
     LMNNRIFFQH PDLMRLLSVH ENVMTIMMNI LTAQQGAAEH DGGEEGMDQS THKDCSEMVV
     ACSRFLCYFC RTSRHNQKAM FEHLSFLLDN ATMLLARPSL RGSVPLDVAY SSFMDNNELA
     LALKEEELDK VTVYLSRCGL QPNSELITKG YPDIGWDPVE GERYIDFLRF CVWINGENVE
     ENANLVIRLL IRRPECLGVA LKGEGQGLFA AFKEAIALSE DIRIIEEAQG GAVHGLKSPL
     LQESQTYPNP ETEGEDYIDL GAATLDFYSS LVDLLAKCAP DPLTIQAGKG DSVRARAILR
     SLISLDDLGH ILSLRFVIPN LNTPNTVDGA YPSQMLPKTS NCCYATHNFS FAALAAEMHT
     AQKISAFPTN NQPVEKSKSE KKIAPVKGIR RHMTKTKSVE ASSSATSSIR TSSSTTDVIG
     SVSTKTNSID KGDKLILPEK RKLKKTISQA VIDSKWTPKK GKRPRLQRMQ RIQQSPAYGR
     NEEYTGPQPG LLPNHKQSVL LFLDRVYGID SQEMLFDLLE NSFLPDLRAA TMMDSVRPRA
     LESDTALALN RYLCNAVLPL LTAHAHFFTD AEHHSALLDA ILHTVYRMNR LKSLTKNQRD
     AKQQQ
//
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