ID H3GH74_PHYRM Unreviewed; 1857 AA.
AC H3GH74;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra75244, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra75244}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra75244};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS566008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 164328.H3GH74; -.
DR EnsemblProtists; Phyra75244; Phyra75244; Phyra75244.
DR VEuPathDB; FungiDB:PSURA_75244; -.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_000604_19_1_1; -.
DR InParanoid; H3GH74; -.
DR OMA; AQEPLHS; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IBA:GO_Central.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 159..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 972..990
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1096..1118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1150..1169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1181..1202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1214..1234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1254..1275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1333..1352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 579..814
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1403..1651
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1369..1401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1857 AA; 202179 MW; AF31279614038930 CRC64;
MYSHFNQSQQ LNLSAHSGIR FAAAMADAGG SSDDAESATL TALSDCVATV LENDISYGLC
VTNSGLFDLV PSQLQGNNTN ASSSSSSSSS SNEFNGDSVC RILCSKLSTS ASSSCCDAAA
SLQSCNTTSS AVTSCKELFD SVFTYQNECD GGLSSANTIL IAVVVVVVAV AASFALLSRC
YGRSQGLAAK VAATCRQIAN LVWKNLVLRR RRPVSLALEI LLPVLLASAL LVLANLDNFA
GGWRASWFTS EAAVLDANET LICSDVVVWG LETIGGPSST MTSFFSGGQS VLGLFFLVSY
IKFVSTTTTT MVIEKENRLR EVMKIMGLSD ATLLCSWCVT TALLSTPLAF AIAAELKYGN
VFPTTEYATL VFLFWTLSVA ITAFSYFVAP FFNKSRTAAI ASVLLWLILF FPYFAVQSAD
TNGPRYWAAL APPTAFALAI DEILRRAQLG TGFAYSVGLR EEPVTVPSAF RMSLFLILDS
VILVALGWYL EQVLPQQYGI RKPWYFLFTK SYWFNKIDHE PASAEEQTTP SLSPQAGGVY
TQLTDGKITV QTLEVEPGNA YVEPVNATLA VQERNGTCLQ IRGLRKVFPL EEDGEEHVAV
AGLDLAMYSG QITALLGHNG AGKTTIISML TGLIPPTAGD ATLYGCSIKR DFHELRRVIG
ICPQHDVLFQ DLTVEEHMLL FGTMKQVPRH KLQSSVDKMI EDVGLTEIRN ALAKTLSGGQ
KRKLSVALAF LGGSKLVFLD EPTSGMDPYS RRFTWNLLQQ SREDRVIVLT THFMDEADIL
GDRIAILADG QLRCAGSSLF LKNRFGAGYN LTMIKTSNGS CDVHLVQSFL KKYVPGVKCL
SSSGSELVFQ LPTASSEAFP AMLEHLDTEM HELGVQQYGI SVTTLEEVFL RISQDHDQQQ
EQHEADGEVV SSLLERKPSA SVVGRTSLKL VSATGVVNLP STAPPITEPT MWMQYVALMK
KRFQIAKRDK KTLAYSVGIP LIFLIILAIL PEIQVADFIP NYTSNLPTDA QQSQCAASTN
FSSLVDADYN VSSCMSFRGF DYCTLGVIDC DVNVCCDAAN IASPWYPCNT CGSSPCYNNN
CLAKNNAKLQ VTLNGFLIAL VVMLAFAFIP AAIVAFVVRE KDPIQNAKSL QLISGANVSA
YWMANWTHDL LLTIIPIVAA AIIIPLSMVP SGAANASSAD VFAVIVLVIA HVWAIIPLAY
LFSRRYVKHA VAQTALLVFA LGTGGLLSIF SFMCRIVNFT ISGSLTLSSL DQNYFRWIFM
IFPGYTLNNG IFELATRKVS RRAMFGSARW LQASPSFFGL FEGLGKEECM ECWDRNDPSC
CVRQPFDLEI VGAPLMYTVV EAVVLSVLVF VLENRSVRWN QTGASQDEKA VHSAVGVDAA
DTADEEEDDD VQRERQRVEH EAPQTNDLVF IRNLRQQYAG KPRAKVALKD LCLSIQSGEC
FGYLGINGAG KSTTMAVLTG QLAPTQGFVT LSGFDLSTSS AAARKTMGYC PQFDALHDLL
TVKEQLELYA RIKGIPEAFV NTAVDEQIQE LGLSKYRDKL TQGLSGGNKR KVSTAIALLG
RPRVVFLDEP STGVDPSSRR KMWDVIARVC STDKDDNRDG GACVVLTTHS MEECEALCSR
VGILVSGRLK CLGSVEHLKQ KFGRGYTVEI TLRALTSSVN ADNTELKSVT DQVLAFLSAE
RSLSARRSER SSQRQSSINT ATNGGAKVTS ANIQELCIVL GAPERGSSIL DHTGTGWLLG
SQLEAQGAIS VDSFCSWWVS ETHGEKLQKF FHDKFPGSVL AEQQGEHFRF QVPKLRPDSS
DGSAALRPAE IFRALEHTRS DLNVDEYSVS ETALEHIFNN MAAQQDEEKG VAHGMYQ
//
