ID H3GL50_PHYRM Unreviewed; 1091 AA.
AC H3GL50;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra77065, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra77065}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra77065};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; DS566019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3GL50; -.
DR EnsemblProtists; Phyra77065; Phyra77065; Phyra77065.
DR VEuPathDB; FungiDB:PSURA_77065; -.
DR eggNOG; KOG0017; Eukaryota.
DR HOGENOM; CLU_000384_38_1_1; -.
DR InParanoid; H3GL50; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 3.10.20.370; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005238}.
FT DOMAIN 617..781
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 65..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1091 AA; 123978 MW; 7C3F67615E8333DB CRC64;
MAFQARWREL KRVGWTSRRP AGLSNDFFYI KPGKTKQGTR GEDYFVGENE LMGYLDRVNI
AERDRQQKEG DAAGPDVATD RLESPPERTD HSKDLDQTQS RAPLERTPPA DMSSRRNLSN
LFDLADSDIN YEDSERGTNQ EIYHWNVAPM GLAGMPATWT RLMHNCFVST SCTHVPTSVI
SASALLIFLV TRSRSTVYTW TRAIAEWMEP SNIKDLQRFL GLVGYYHRFI HRFATLVLPL
SALVKMDVPW AWDDTLRLSF NAIKLTLQHP PVLRLPDFDR PFIVTTDAGH ACTGGVLSQL
HDGSDIPVAF FSKKLGPHEL NWPVHEKELF AIKQALTRWR HYLHGVSFEV YTDNSACKWF
LQHPRLFGRL ARWLDFFASF QFTLHHRPGA MNVIADALSR PPGPSSSLGE GQDDNESKPV
TVSLCAACRS SPTCTDIRQA ASRRTKTTEK IRSIPTRDQD VILAVKQPVA ELHDVGTAQL
RMRVHAFSTA GSTVISSLQL DTQTKKAFQK AYDRDPEFKH LWKYGRTSEE YEVVHGLVYL
KSNDNLRRLC VPTNRKLRVD VIHTTHDAAI MAHPGIRRTQ LAAAQWYFWP SMDLDIKSDV
QSCESCMRYK GRKTGKLQPI PLPAACWEVA STDFITHLPV SDGFDAIMVV VDKLSKRPVY
IPTHTMATAE DTAKLFFNNV IRYYGIPSTI TSDRDPKFTS RFWTALVNLM MIKAAMTSAH
RAQADGQTER QNRTLEDSLR CSISYHGNDW NEHLPMIEYA HATLVSSSST LSPFFVDTGR
KPTNPLDTGA DAASVPRSRV EHASRFVQHR QEVIERARKN LLDAQAAQKK FYDKRRAENP
FKVGDHALLS TQDLNISHAT AETTLRSRKF IPCFIGPYTI LEIRGNVALL DLPANLKSLS
PRFNIDKVKV YTSNPDRFDG RVIPKSIPVI FDDDGEPLHV VEALIKRRTF NRQPEYLVRW
HGLPHHRNTT VTSSMSVTGK RCSKIYAAAL KHGPSVIFFM RGFPVMFLTT RDYGTINFNF
DDFIFKVLGL AQLGESVTIC KYKSRATRHH QESPHREPRS MPAYSRRLRK HAPRRTIANH
CMFKSALPAR S
//
